Jurnal pangan nasional "terakreditasi" Kemeristekdikti dari Indonesian Food Technologists® - IFT

DOI: https://doi.org/10.17728/jatp.7276

Pengaruh Pemberian Cookies Galohgor terhadap Kadar Vitamin A ASI Ibu Nifas

Ibnu Malkan Bakhrul Ilmi  -  Program Studi Ilmu Gizi, Fakultas Ilmu Kesehatan, Universitas Pembangunan Nasional Veteran, Jakarta, Indonesia
*Rimbawan Rimbawan scopus  -  Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, IPB University, Bogor, Indonesia
Katrin Roosita scopus  -  Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, IPB University, Bogor, Indonesia
Zakiudin Munasir scopus  -  Departemen Ilmu Kesehatan Anak, Fakultas Kedokteran, Universitas Indonesia, Jakarta, Indonesia

Citation Format:
Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian cookies galohgor terhadap kadar β-karoten dan retinol ASI ibu nifas. Penelitian ini menggunakan quasi-experimental design yang terdiri atas dua kelompok, yaitu kelompok kontrol (n=9) dan kelompok intervensi (n=9). Kelompok intervensi diberikan cookies galohgor 4 keping ~ 40 g/ hari, sedangkan kelompok kontrol diberikan cookies dengan jumlah yang sama namun cookies tersebut tanpa penambahan galohgor. Pemberian cookies dilakukan selama 40 hari pascamelahirkan. Sampel ASI diambil pada hari ke-14 dan hari ke-40 untuk dianalisis kadar β-karoten dan retinol ASI. Analisis konsumsi pangan juga dilakukan bersamaan dengan pengambilan sampel ASI. Hasil penelitian ini menunjukkan tidak terdapat perbedaan pada kadar β-karoten dan retinol ASI antara kelompok kontrol dan intervensi, baik pada hari ke-14 maupun hari ke-40 pascamelahirkan (p>0,05), akan tetapi pemberian cookies galohgor relatif dapat mempertahankan kadar β-karoten ASI selama masa nifas. Oleh karena itu, penelitian ini menyimpulkan cookies galohgor dapat menjadi sumber β-karoten ASI.

Effect of Galohgor Cookies on Vitamin A Content in Breast Milk of Postpartum Mothers

Abstract

This study was aimed to analyze the effect of galohgor cookies on β-carotene and retinol in breast milk of postpartum mothers. This study used quasi-experimental design consisting of two groups, the control group (n = 9) and the intervention group (n = 9). The intervention group was given galohgor cookies (4 pieces ~ 40 g / day), while the control group was given cookies without galohgor as many as the intervention group. Cookies were given for 40 days after giving birth. Breast milk samples were taken on the 14th day and 40th day to analyze β-carotene and retinol content in breast milk along with the interview of food consumption. The results showed β-carotene and retinol content in breast milk did not differ significantly between the groups, both on the 14th day and the 40th day after giving birth (p>0.05). However, galohgor might maintain the β-carotene concentration in breast milk. Therefore, as conclusion, galohgor cookies may be provided as the source of β-carotene in breast milk.

Fulltext View|Download
Keywords: ASI; β-karoten; cookies galohgor; ibu nifas; retinol; β-carotene, breast milk, galohgor cookies, postpartum mother, retinol
Funding: Lembaga Pengelola Dana Pendidikan (LPDP) Kementerian Keuangan Republik Indonesia

Article Metrics:

Article Info
Section: Artikel Penelitian (Research Article)
Language : ID
Recent articles
Pembuatan nanopartikel pati jagung dengan teknik fotooksidasi menggunakan H2O2 dan lampu UV-C pada sistem tersirkulasi Pengolahan Sinbiotik Kultur Campuran yang Berasal dari Kombinasi Bekatul Gandum sebagai Prebiotik dan Jus Kubis Terfermentasi sebagai Probiotik melalui Proses Fermentasi Optimasi Karakteristik Tepung Komposit Berbasis Tepung Onggok Fermentasi menggunakan Metode Response Surface Methodology (RSM) More recent articles
  1. Aaran, R. K., Nikkari, T. 1988. HPLC method for the simultaneous determination of beta-carotene, retinol and alpha-tocopherol in serum. Journal of Pharmaceutical and Biomedical Analysis 6(6-8):853-857. DOI: 10.1016/0731-7085(88)80101-8
  2. Ballard, O., Morrow, A.L. 2013. Human milk composition: nutrients and bioactive factors. Pediatric Clinics 60(1):49-74. DOI: 10.1016/j.pcl.2012.10.002
  3. Bolisetty, S., Naidoo, D., Lui, K., Koh, T.H.H.G., Watson, D., Montgomery, R., Whitehall, J. 2002. Postnatal changes in maternal and neonatal plasma antioxidant vitamins and the influence of smoking. Archives of Disease in Childhood-Fetal and Neonatal Edition 86(1):F36-F40. DOI: 10.1136/fn.86.1.f36
  4. Canfield, L.M., Clandinin, M.T., Davies, D.P., Fernandez, M.C., Jackson, J., Hawkes, Goldman, W.J., Pramuk, K., Reyes, H., Sablan, B., Sonobe, T., Bo, X. 2003. Multinational study of major breast milk carotenoids of healthy mothers. European Journal of Nutrition 42(3):133-141. DOI: 10.1007/s00394-003-0403-9
  5. Chakravarty, I. 2000. Food-based strategies to control vitamin A deficiency. Food and Nutrition Bulletin 21(2):135-143. DOI: 10.1177%2F156482650002100205
  6. Christian, L.M., Porter, K. 2014. Longitudinal changes in serum proinflammatory markers across pregnancy and postpartum: effects of maternal body mass index. Cytokine 70(2):134-140. DOI: 10.1016/j.cyto.2014.06.018
  7. Damayati, R.P., Roosita, K., Sulaeman, A. 2018. Effect of galohgor cookies and powder drinks on visceral adipose tissue and lipid profile in patients with type 2 diabetes mellitus. Jurnal Gizi dan Pangan 13(3):137-144. DOI: 10.25182/jgp.2018.13.3.137-144
  8. Daniels, L., Gibson, R.S., Diana, A., Haszard, J.J., Rahmannia, S., Luftimas, D.E., Hampel, D., Shahab-Ferdows, S., Reid, M., Lammers, Y., Allen, L.H., Houghton, L.A. 2019. Micronutrient intakes of lactating mothers and their association with breast milk concentrations and micronutrient adequacy of exclusively breastfed Indonesian infants. American Journal of Clinical Nutrition 110(2):391-400. DOI: 10.1093/ajcn/nqz047
  9. Dijkhuizen, M.A., Wieringa, F.T., West, C.E. 2004. Zinc plus β-carotene supplementation of pregnant women is superior to β-carotene supplementation alone in improving vitamin A status in both mothers and infants. The American Journal of Clinical Nutrition 80(5):1299-1307. DOI: 10.1093/ajcn/80.5.1299
  10. Dror, D.K., Allen, L.H. 2018. Overview of nutrients in human milk. Advances in Nutrition 9(suppl_1):278S-294S. DOI: 10.1093/advances/nmy022
  11. Gonçalves, A., Estevinho, B. N., Rocha, F. 2016. Microencapsulation of vitamin A: A review. Trends in Food Science & Technology 51:76-87. DOI: 10.1016/j.tifs.2016.03.001
  12. Gossage, C.P., Deyhim, M., Yamini, S., Douglass, L.W., Moser-Veillon, P.B. 2002. Carotenoid composition of human milk during the first month postpartum and the responses to β-carotene supplementation. The American Journal of Clinical Nutrition 76(1):193-197. DOI: 10.1093/ajcn/76.1.193
  13. Hadi, H., Stoltzfus, R.J., Dibley, M. J., Moulton, L.H., West Jr, K.P., Kjolhede, C.L., Sadjimin, T. 2000. Vitamin A supplementation selectively improves the linear growth of Indonesian preschool children: results from a randomized controlled trial. The American Journal of Clinical Nutrition 71(2):507-513. DOI: 10.1093/ajcn/71.2.507
  14. Haskell, M.J., Brown, K.H. 1999. Maternal vitamin A nutriture and the vitamin A content of human milk. Journal of Mammary Gland Biology and Neoplasia. 4(3):243-257. DOI: 10.1023/A:1018745812512
  15. Herman, S. 2007. Masalah kurang vitamin A (KVA) dan prospek penanggulangannya. Media Litbang Kesehatan 4:40-44. DOI: 10.22435/mpk.v17i4Des.824
  16. Holt, E.M., Steffen, L.M., Moran, A., Basu, S., Steinberger, J., Ross, J.A., Hong, C., Sinaiko, A.R. 2009. Fruit and vegetable consumption and its relation to markers of inflammation and oxidative stress in adolescents. Journal of the American Dietetic Association 109(3):414-421. DOI: 10.1016/j.jada.2008.11.036
  17. Innis, S. M. 2014. Impact of maternal diet on human milk composition and neurological development of infants. The American Journal of Clinical Nutrition 99(3):734S-741S. DOI: 10.3945/ajcn.113.072595
  18. Jokar, N.K., Noorhosseini, S.A., Allahyari, M.S., Damalas, C.A. 2017. Consumers' acceptance of medicinal herbs: an application of the technology acceptance model (TAM). Journal of Ethnopharmacology 207:203-210. DOI: 10.1016/j.jep.2017.06.017
  19. Keikha, M., Bahreynian, M., Saleki, M., Kelishadi, R. 2017. Macro-and micronutrients of human milk composition: Are they related to maternal diet? A comprehensive systematic review. Breastfeeding Medicine 12(9):517-527. DOI: 10.1089/bfm.2017.0048
  20. Lemeshow, S., Hosmer, D. W., Klar, J., Lwanga, S.K., World Health Organization. 1990. Adequacy of Sample Size in Health Studies. Wiley, Chichester
  21. Lönnerdal, B.O. 1986. Effects of maternal dietary intake on human milk composition. The Journal of Nutrition 116(4):499-513. DOI: 10.1093/jn/116.4.499
  22. Ma’rifah, B., Roosita, K., Sinaga, T. 2019. The galohgor nutraceutical cookies effects on β-carotene serum and oxidative stress of postpartum mothers. Preventive Nutrition and Food Science 24(4):381-386. DOI: 10.3746/pnf.2019.24.4.381
  23. Macy, I.G. 1949. Composition of human colostrum and milk. American Journal of Diseases of Children 78(4):589-603. DOI: 10.1001/archpedi.1949.02030050604009
  24. Maden, M. 2007. Retinoic acid in the development, regeneration and maintenance of the nervous system. Nature Reviews Neuroscience 8(10):755-765. DOI: 10.1038/nrn2212
  25. Mao, Y., Ling, P.R., Fitzgibbons, T.P., McCowen, K.C., Frick, G.P., Bistrian, B.R., Smith, R.J. 1999. Endotoxin-induced inhibition of growth hormone receptor signaling in rat liver in vivo. Endocrinology 140(12):5505-5515. DOI: 10.1179/2046905514Y.0000000134
  26. Mitoulas, L.R., Kent, J.C., Cox, D.B., Owens, R.A., Sherriff, J.L., Hartmann, P.E. 2002. Variation in fat, lactose and protein in human milk over 24h and throughout the first year of lactation. British Journal of Nutrition 88(1):29-37. DOI: 10.1079/BJN2002579
  27. Muhilal, P.D., Idjradinata, Y.R., Muherdiyantiningsih, K.D. 1988. Vitamin A-fortified monosodium glutamate and health, growth, and survival of children: a controlled field trial. American Journal of Clinical Nutrition 48(5):1271-1276. DOI: 10.1093/ajcn/48.5.1271
  28. Muslimatun, S., Schmidt, M. K., West, C. E., Schultink, W., Hautvast, J. G., Karyadi, D. 2001. Weekly vitamin A and iron supplementation during pregnancy increases vitamin A concentration of breast milk but not iron status in Indonesian lactating women. Journal of Nutrition 131(10):2664-2669. DOI: 10.1093/jn/131.10.2664
  29. Noor, N., Islam, N., Moin, S., Mahdi, A.A., Jaiswal, S., Bano, F. 2008. Normal delivery induced stress alters glutathione peroxidase and TNF-α in elderly primigravidas mononuclear cells. Indian Journal of Clinical Biochemistry 23(3):227-232. DOI: 10.1007/s12291-008-0051-1
  30. Rice, A.L., Stoltzfus, R.J., de Francisco, A., Chakraborty, J., Kjolhede, C.L., Wahed, M.A. 1999. Maternal vitamin A or β-carotene supplementation in lactating Bangladeshi women benefits mothers and infants but does not prevent subclinical deficiency. The Journal of Nutrition 129(2):356-365. DOI: 10.1093/jn/129.2.356
  31. Roosita, K. 2014. Peranan β-karoten dan nutraseutikal galohgor dalam proliferasi, diferensiasi, dan ekspresi gen sel epitel usus (CMT-93) dan sel kelenjar mammae (HC11). Disertasi, Institut Pertanian Bogor, Bogor
  32. Roosita, K., Kusharto, C.M., Kusumorini, N., Manalu, W. 2003. The effect of traditional herbs medicine “Galohgor” on uterus involution and milk production of rats (Rattus sp.) made in Sukajadi Village, Tamansari Subdistrict, Bogor, Indonesia. Proceedings, Symposium Series 1. International Symposium on Biomedicines: Biodiversity on Traditional Biomedicines for Human Health and Welfare. Biopharmaca Research Center, Bogor Agricultural University, Bogor, Indonesia, September 18-19. Page 18-19
  33. Roosita, K., Rimbawan, S.M., Djuwita, I., Damanik, M.R., Kusharto, C.M., Damayanthi, E., Nomura, N. 2014. β-carotene roles in proliferation and differentiation, connexin and β-casein gene expression of mammary gland cells line. Malaysian Journal of Nutrition 20(1):113-119. DOI: 10.5935/abc.20130160
  34. Ros, H.S., Lichtenstein, P., Bellocco, R., Petersson, G., Cnattingius, S. 2001. Increased risks of circulatory diseases in late pregnancy and puerperium. Epidemiology 12(4):456-460. DOI: 10.1097/00001648-200107000-00016
  35. Sandjaja, S., Budiman, B., Harahap, H., Ernawati, F., Soekatri, M., Widodo, Y., Sumedi, E., Rustan, E., Sofia, G., Syaried, S.N., Khouw, I. 2013. Food consumption and nutritional and biochemical status of 0• 5–12-year-old Indonesian children: the SEANUTS study. British Journal of Nutrition 110(S3):S11-S20. DOI: 10.1017/S0007114513002109
  36. Schauberger, C,W., Rooney, B.L., Brimer, L.M. 1992. Factors that influence weight loss in the puerperium. Obstetrics and Gynecology 79(3):424-429. DOI: 10.1097/00006250-199203000-00020
  37. Schweigert, F.J., Bathe, K., Chen, F., Büscher, U., Dudenhausen, J.W. 2004. Effect of the stage of lactation in humans on carotenoid levels in milk, blood plasma and plasma lipoprotein fractions. European Journal of Nutrition 43(1):39-44. DOI: 10.1007/s00394-004-0439-5
  38. Setyaningsih, S., Katrin, R., Damayanthi, E. 2017. Efek produk galohgor terhadap aktivitas antioksidan dan penurunan stres oksidatif Diabetes Melitus tipe 2. Media Kesehatan Masyarakat Indonesia Universitas Hasanuddin 13(4):310-318. DOI: 10.30597/mkmi.v13i4.1930
  39. Stoltzfus, R. J., Hakimi, M., Miller, K. W., Rasmussen, K. M., Dawiesah, S., Habicht, J. P., Dibley, M. J. 1993. High dose vitamin A supplementation of breast-feeding Indonesian mothers: effects on the vitamin A status of mother and infant. Journal of Nutrition 123(4):666-675. DOI: 10.1093/jn/123.4.666
  41. Strobel, M., Tinz, J., Biesalski, H. K. 2007. The importance of β-carotene as a source of vitamin A with special regard to pregnant and breastfeeding women. European Journal of Nutrition 46(9):1-20. DOI: 10.1007/s00394-007-1001-z
  42. Tanaka, M., Kamiya, Y., Suzuki, T., Kamiya, M., Nakai, Y. 2008. Relationship between milk production and plasma concentrations of oxidative stress markers during hot season in primiparous cows. Animal Science Journal 79(4):481-486. DOI: 10.1111/j.1740-0929.2008.00553.x
  43. Zarban, A., Taheri, F., Chahkandi, T., Sharifzadeh, G., Khorashadizadeh, M. 2009. Antioxidant and radical scavenging activity of human colostrum, transitional and mature milk. Journal of Clinical Biochemistry and Nutrition 45(2):150-154. DOI: 10.3164/jcbn.08-233
  44. Zhao, Y., Xiao, X., Frank, S.J., Lin, H.Y., Xia, Y. 2014. Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-α, and IL-1β. American Journal of Physiology-Endocrinology and Metabolism 307(2):E186-E198. DOI: 10.1152/ajpendo.00652.2013

Last update:

No citation recorded.

Last update:

No citation recorded.