DOI: https://doi.org/10.14710/jbtr.v6i3.8451

Neuromyelitis Optica (NMO) in Children: A Rare Case Report

Faculty of Medicine, Diponegoro University, Indonesia

Received: 9 Jul 2020; Revised: 31 Oct 2020; Accepted: 24 Nov 2020; Available online: 31 Dec 2020; Published: 31 Dec 2020.
Open Access Copyright (c) 2020 Journal of Biomedicine and Translational Research

Citation Format:
Abstract

Background: Neuromyelitis optica (NMO) is a rare autoimmune disease that covers 20-30% of diseases related to autoimmune disorders and about 1% of demyelination diseases. NMO symptoms are vary between individuals, there are generally 2 main symptoms, transverse myelitis and optic neuritis. This article reported a child with NMO disease based on The Consensus of the International Panel for NMO Diagnosis (IPND) 2015.

Case Presentation: An 8-year old boy with spastic tetraparesis, bilateral nervus opticus dysfunction, urinary retention, and allodynia et causa suspected NMO. Patient received therapy using high-dose intravenous methylprednisolone and showing a clinical improvement.

Conclusion: This patient was diagnosed NMO based on IPND 2015 with an unknown AQP4-Ab status accompanied by supporting clinical symptoms. The management of NMO with high-dose intravenous methylprednisolone in this patient provides a meaningful response to the clinical improvement of the disease.

 

Note: This article has supplementary file(s).

Fulltext View|Download |  Research Instrument
Cover Letter
Subject
Type Research Instrument
  Download (21KB)    Indexing metadata
 common.other
Copyright
Subject
Type Other
  Download (455KB)    Indexing metadata
Keywords: neuromyelitis optica; autoimmune; methylprednisolone

Article Metrics:

Article Info
Section: Case Reports
Language : EN
Recent articles
Comparison of Very Low Birth Weight Preterm Infants with And Without Experienced Target Weight Gain on The Administration of Human Milk Fortifier Peanut (Arachis hypogaea) Shells Extract and Apis dorsata Honey Reduce Matrix Metalloproteinase-3 in Monosodium Iodoacetate-Induced Osteoarthritic Rats The Effect of Glutathione on Serum Malondialdehyde (MDA) Level in Retinopathy of Prematurity Rat Models SRY-negative in 46, XX Male Testicular DSD: a case report Neuromyelitis Optica (NMO) in Children: A Rare Case Report Radiotherapy for Recurrent Keloid: A Case Report Hyperuricemia as a Risk Factor for Cardiovascular Diseases Cyclic nucleotide in oocyte In vitro maturation in Assisted Reproductive Technology More recent articles
  1. Huda S, Whittam D, Bhojak M, Chamberlain J, Noonan C, Jacob A, et al. Neuromyelitis optica spectrum disorders. Clin Med. 2019; 19(2):169-176
  2. Kim WB, Lee SY, Kim BR, Kim YJ. Rehabilitation of neuromyelitis optica. Medicine. 2019; 98(41):1-5
  3. Lana-Peixoto MA, Talim N. Neuromyelitis Optica Spectrum Disorder and Anti-MOG Syndromes. Biomedicines. 2019;7(2):1-24
  4. Bertado CB, Martinez CCE, Martinez MM. Devic’s disease: A case report and literature review. Rev Fac Med UNAM. 2018;61(1):26-32
  5. Chi LM, Gao Y, Nan G. A case report of neuromyelitis optica spectrum disorder with peripheral neuropathy as the first episode. Medicine. 2018; 97(10):1-3
  6. Medina RR, Sanchez JA, Bertado CB, Martinez CCE, Martinez MM. Devic’s disease: A case report and literature review. Rev Fac Med UNAM. 2018;61(1):26-32
  7. Waheed S, Hussian J, Saood Y, Shehzadi A. Neuromyelitis Optica (NMO): A Case Report. PJNS. 2018; 13(3): 21-26
  8. Badri N, Teleb M, Syed S, Wardi M, Porres-Agular M, Cruz-Flores S. Seronegative Neuromyelitis Optica: A Case Report of a Hispanic Male. Case Rep Neurol. 2016; 8:102-107
  9. Gurgen N, Yalcin D, Gozukizil ST, Polisci D. Neuromyelitis Optica: Case Report. SETB. 2016; 50(2): 166-170
  10. Sepulveda M, Armangue T, Sola-Valls N, Arrambide G, Meca-Lallana JE, Oeeja-Guevara C, et al. Neuromyelitis Optica Spectrum Disorders: Comparison According to the Phenotype and Serostatus. Neurol Neuroimmunol Neuroinflamm. 2016;3(3):1-11
  11. Sudulagunta SR, Sodalagunta MB, Khorram H, Sepehrar M and Noroozpour Z. Neuromyelitis optica (NMO). SM J Clin Med Imaging. 2015; 1(1): 1-5
  12. Pereira WLDC, Reiche EMV, Kallaur AP, Maciel DRK. Epidemiological, clinical, and immunological characteristics of neuromyelitis optica: A review. J Neurol Sci. 2015; 355(1-2): 7-17
  13. Huang TL, Lin KH, Wang JK, Tsai RK. Treatment strategies for neuromyelitis optica. Tzu Chi Med J. 2018; 30(4): 204-208
  14. Weinshenker BG, Wingerchuk DM. Neuromyelitis Spectrum Disorders. Mayo Clin Proc. 2017; 92(4): 663-679
  15. Pandit L, Asgari N, Apiwattanakul M, Palace J, Paul F, Leite MI, et al. Demographic and clinical features of neuromyelitis optica; A review. Mult Scler. 2015;21(7):845-853
  16. Ochi H, Fujihara K. Demyelinating diseases in Asia. Curr Opin Neurol. 2016;29(3):222-228
  17. Tapiheru LA, Sinurat PPO, Ritarwan K. Myelitis transversa. JMS. 2007; 40(3): 230-236
  18. Hoorbakht H, Bagherkashi F. Optic Neuritis, its Differential Diagnosis and Management. Open Ophthalmol J. 2012; 6: 65-72
  19. Menon V, Saxena R, Misra R, Phuljhele W.Management of optic neuritis. Indian J Ophthalmol. 2011; 59: 117-122
  20. Wilhelm H, Schabet M: The diagnosis and treatment of optic neuritis. Dtsch Arztebl Int. 2015; 112: 616-626
  21. Hidayat M. Clinical Profile of Bilateral Optic Neuritis. JKA. 2018; 7 (Supplement 1): 17-23
  22. Cree B.C. Handbook of Clinical Neurology. Netherland: Elsevier; 2014
  23. Aninditha T, Wiratman W. Buku Ajar Departemen Neurologi. Jakarta: Penerbit Kedokteran Indonesia; 2017
  24. Dutra BG, Rocha AJD, Nunes RH, Junior ACMM. Neuromyelitis Optica Spectrum Disorders: Spectrum of MR Imaging Findings and Their Differential Diagnosis. Radiographics. 2018;38(1):169-193
  25. Wingerchuk DM, Banwell B, Bennett JL. Cabre P, Carroll W, Chitnis T. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology. 2015;85(2):177-189

Last update:

No citation recorded.

Last update:

No citation recorded.