DOI: https://doi.org/10.14710/jbtr.v5i1.3711

Prevalence of Malaria Parasites among Pregnant Women and Children under Five years in Ekiti State, Southwest Nigeria.

1The Federal University of Technology, Nigeria

2University of Sains Malaysia, Malaysia

Received: 23 Nov 2018; Accepted: 23 Mar 2019; Available online: 25 Jul 2019; Published: 31 Jul 2019.
Open Access Copyright (c) 2019 Journal of Biomedicine and Translational Research

Citation Format:
Abstract

Background: Malaria is a deadly disease causing serious public health issues among pregnant women and children worldwide especially in tropical and subtropical Africa. This study was carried out to determine the prevalence of malaria parasites among pregnant women and children under five years in Ekiti State, Nigeria.

Methodology: A total of 380 blood samples were collected from the pregnant women and children under five years respectively. Malaria parasites were examined microscopically on thick and thin blood smear stained with Giemsa stain while personal data were collected through questionnaire and confirmed from file records. Red cell phenotyping was carried out manually with standard tube technique for blood group. Haemoglobin electrophoresis was carried out using the cellulose acetate alkaline haemoglobin electrophoresis technique, which allowed for the separation of haemoglobin A, F, S, and C into distinct bands.

Results: The results showed that of 380 pregnant women sampled, 153 (40.2%) were positive for malaria parasites and 63 (63%) were positive of the 100 children sampled. The highest prevalence of malaria parasites 18 (51.4%) and 25 (71.4%) were observed in ages 36-39 and <1 years for pregnant women and children respectively. Multigravidae was 1.19 times (95% Cl: 0.77, 1.84) more vulnerable to malaria compare to primigravidae. Women in the first trimester were more infected with malaria parasites 40 (75.4%) than those in second trimester 46 (23.3%) and third trimester 67 (51.9%). Among children under five years of age, females 38 (66.7%) had the highest prevalence compared to males 25 (58.1%). However, there was no significant difference. Statistical analysis showed a significant difference in genotype types (P<0.05).

Conclusion: This study revealed that malaria infection is still endemic in the study area, hence, there is urgent need to deploy management strategy to the study area.

Note: This article has supplementary file(s).

Fulltext View|Download |  Research Instrument
Cover Letter
Subject
Type Research Instrument
  Download (40KB)    Indexing metadata
 Research Instrument
Names of potential Reviewers
Subject
Type Research Instrument
  Download (16KB)    Indexing metadata
Keywords: Plasmodium falciparum; blood group; Genotype; Children; Pregnant women
Funding: sponsored by authors

Article Metrics:

Article Info
Section: Original Research Articles
Language : ENGLISH
Recent articles
Phlebotrophic Effect of Graptophyllum Pictum (L.) Griff on Experimental Wistar Hemorrhoids Validation of Self-Reported Smoker and Second Hand Smoke Exposure by Urinary Cotinine within The Malaysian Cohort Project A long-term follow-up of Sex Chromosomal Mosaicism Disorders of Sex Development Fragile X syndrome, the search for a targeted treatment Seroprevalence of Hepatitis B and C in Healthy Malaysian Adults: A Preliminary Report More recent articles
  1. World Health Organisation (2015). Factsheet on the World Malaria Report 2014
  2. Ekanem OJ, Weisfield JS, Salako LA, Nahles BL, Ezedinachi EN (1999). Sensitivity of Plasmodium falciparum to chloroquine and Sulphadoxine/ Pyrimethamine in Nigeria Children. Bulletin of World Health Organization. 68(1): 45-52
  3. Getaneh Alemu and Mohammedaman Mama (2016). Assessing ABO/Rh blood group frequencyin association with asymptomatic Malria among blood donors attending Arba Minah blood bank, South Ethiopia. Malaria Research and Treatment (2016); 1-7
  4. Jimoh A, Sofola O, Petu A,Okorosobo T (2007). Quantifying the economic burden of infection in Nigeria using the willingness to pay approach. Cost Eff Resour Alloc; 5:5-6
  5. World Health Organization (WHO) (2008). Blood Transfusion Safety. Regional Meeting of Directors of Blood Transfusion Services Sharja, United Emirates. World Health Organization, Information Sheet; 15-17
  6. Adefioye OA, Adeyeba, OA Hassan WO, Oyeniran OA (2007). Prevalence of Malaria Infection among pregnant women in Osogbo South West Nigeria. American- Eurasian Journal of Scientific Research; 2(1): 43-45
  7. Amodu, OK, Olaniyan SA, Adeyemo AA, Trove-Blomberg M, Olumese PE, Omotade OO (2012). Association of Sickle cell trait and the ABO group with clinical severity of malaria in Southwest, Nigeria. Act. Trop 123(2): 72-77
  8. Onyido AE, Agbata VO, Umeanaeto PU, Obiukwu MO, Amadi ES (2010). Malaria burden and vector abundance in Sub Urban Community in the rainforest zone of Nigeria. Nigerian Journal of Microbiology; 24(1): 2224-2230
  9. Opara AU, Nnodim JK, Dike J (2011). Prevalence of malaria among rural farmers of North Central Area of Ebonyi State Nigeria. International Science Research Journal; 3:29-33
  10. Charles Okot Odongo, Michael Odida, Henry Wabinga, Celestino Obua and Jehosaphat Byamugislic (2016). Burden of placental malaria among pregnant women who use or do not use intermittent preventive treatment at Mulago Hospital, Kampala. Malaria Research and Treatment (2016); 8-14

Last update:

No citation recorded.

Last update:

No citation recorded.