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Efek Antifeedant Umpan Blok Singkong (Manihot esculenta) terhadap Perubahan Bobot Badan Tikus Putih (Mus musculus L.)

Lia Wulandari  -  Port Health Office of Jambi, Indonesia
*Dwi Sutiningsih  -  Universitas Diponegoro, Indonesia
Martini Martini  -  Universitas Diponegoro, Indonesia

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Background: Rodent-borne disease control relies on reservoir control is rodent animals. Controlling techniques are urgent to do, such as biopesticide use. The use of biopesticide should be developed to reduce the negative impact of chemical rodenticides. Manihot esculenta have cyanogenic glycosides with antifeedant effects. The potential of biopesticide used for pest management.

Methods: Block bait consumption of cassava (Manihot esculenta) on body weight of Mus musculus L. was carried out an experimental rat. The objective of the test was to observe the direct effect of cassava block bait on mice. The animal model was divided into six treatment groups (5.75%; 11.5%; 23%; 46%; 92%; 184%) with control. Each treatment group was repeated 5 times. Treatment was given during the 14 days orally. The parameters that were obtained are feed consumption and body weight.

Result: This experiment showed that there was a difference in feed consumption and on body weight mice in all animal model groups.

Conclusion: It concluded that block bait of cassava (Manihot esculenta) in different concentrations has an antifeedant effect, causing alteration on feed consumed and body weight of Mus musculus L.

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Keywords: Block bait; Manihot esculenta; Mus musculus L
Funding: Ministry of Health

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  1. Ghasemi A, Esmaeili S, Shahraki HS, et al. Upsurge of rodents’ population in a rural area of northeastern Iran raised concerns about Rodent-borne diseases. J med Microbiol Infec Dis. 2017; 5 (1-2):21-25
  2. Rabbie MH, Mahmoudi A, Siahsarvie R, et al. Rodent-borne disease and their public health importance in Iran. J Plos Neglected Tropical Diseases. 2018; 12 (4):1-20
  3. Dehghani R, Bidgoli MS, Takhtfiroozeh S, et al. Contamination status of hospitals and health care centers by rodents (Rodentia: Muridae) in Iran. J of Communicable Disease. 2018; 50(2):11-16
  4. Kementerian Kesehatan Republik Indonesia. Profil Kesehatan Indonesia 2015. Jakarta; 2015
  5. Kementerian Kesehatan Republik Indonesia. Profil Kesehatan Indonesia. Jakarta; 2016. Available from:
  6. Kementerian Kesehatan Republik Indonesia. Profil Kesehatan Indonesia 2017. Jakarta; 2018
  7. Eisen, Rebecca J., Russel E, Enscore, Linda A A et al. Evidence that rodent control strategies ought to be improved to enhance food security and reduce the risk of rodent-borne illnesses within subsistence farming villages in the plague-endemic West Nile region, Uganda. Int J Pest Manag. 2013;59(4):259–70
  8. Balitkabi. Deskripsi Varietas unggul ubi kayu. 2017. Available from:
  9. BPS. Luas panen ubi kayu menurut provinsi (ha), 1993-2015. 2017. Available from:
  10. Adeyemo S. Molecular Genetic Characterization of Photoperiodic genes in Cassava (Manihot esculenta Crantz) and attempts to manipulate their expression to promote floral induction. Dissertation. Universität zu Köln; 2009
  11. Cahyawati PN, Sc M, Zahran I, Farm S, Sc M, Jufri MI, et al. Keracunan Akut Sianida. J Lingkung Pembang. 2017;1(1):80–7
  12. Hartati I, Kurniasari L, Yulianto ME. Inaktivasi enzimatis pada produksi linamarin dari daun singkong sebagai senyawa anti neoplastik. J Momentum. 2008; 4(2): 1-6
  13. Ningtyas DAR, Cahyati WH. Uji daya bunuh umpan blok umbi gadung (Dioscorea hispida L) terhadap Tikus. J Kesehat Masy (Journal Public Heal. 2017;11(2):159–64
  14. Langenheim JH, Thimann K V. Botany: plant biology and its relation to human affairs. United States of America: John Wiley & Sons, Inc; 1982
  15. Modupe, Adeyemi M and Mohammed M. Prospect of atifeedant secondary metabolites as post harvest maerial. International Journal of Innovative Research in Science, Engineering and Technology. 2014;3(1):8701-8708
  16. Suckow MA, Weisbroth SH, Frankin CL. The laboratory rat. London: Elsevier Academic Press; 2005

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