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The Effects of Rusip on the Amount of Lactic Acid Bacteria in Gastrointestinal Tract

1Health Office of Kepulauan Bangka Belitung, Indonesia

2Faculty of Medicine Diponegoro University, Indonesia

Received: 24 Nov 2016; Published: 29 Dec 2016.
Open Access Copyright (c) 2016 Journal of Biomedicine and Translational Research

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Background : Rusip consumption can change the microbial composition of the digestive system. Microbial changes due to rusip consumption that is measured by lactic acid bacteria count has not been conducted.

Objective : The purpose of the study was to analyze the effect of rusip consumption to the number of lactic acid bacteria in the gastrointestinal tract.

Methods : Experimental study with post test only control group design using twelve Rattus novergicus Sprague dawley strains aged 2-2.5 months which were divided into 2 groups. Rats adapted for a week, then they were given rusip 5.1 mg/g body weight for 14 days. Cecal content were taken on the 22th day to be analysed for the lactic acid bacteria count.

Results : The number of lactic acid bacteria (LAB) in the group given rusip was lower compared to the control group, but not significantly different (p=0.180). Weight gain was greater in the treatment group compared to the control group. The given group tends to have more weight in cecal content and lower pH compared to the control group.

Conclusion : Rusip consumption does not increase the number of lactic acid bacteria in gastrointestinal tract.

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Keywords: Rusip; cecum; fermentation; lactic acid bacteria; gastrointestinal tract

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  1. Garrett WS, Gordon JI, Glimcher LH. Homeostasis and Inflammation in the Intestine. Cell. 2010;140(6):859-70
  2. Ross RP, Mills S, Hill C, Fitzgerald GF, Stanton C. Specific metabolite production by gut microbiota as a basis for probiotic function. Int Dairy J. 2010;20(4):269-76
  3. Vizoso Pinto MG, Franz CMAP, Schillinger U, Holzapfel WH. Lactobacillus spp. with in vitro probiotic properties from human faeces and traditional fermented products. Int J food microbiol. 2006;109(3):205-14
  4. Tannock GW. Microecology of the gastrointestinal tract in relation to lactic acid bacteria. Int Dairy J. 1995;5(8):1059-70
  5. Chen GY, ez GNn. Gut Immunity: A NOD to the Commensals. Cell. 2008;19(4):R171 - R4
  6. Duerkop BA, Vaishnava S, Hooper LV. Immune Responses to the Microbiota at the Intestinal Mucosal Surface. Immunity. 2009;31(3):368-76
  7. Dore J, Corthier G. The human interstinal microbiota. Gastroen Clin Biol. 2010;34:S7 - S15
  8. Dinan TG, Cryan JF. Regulation of the stress response by the gut microbiota : Implications for psychoneuroendocrinology. Psychoneuen - journal. 2012;37:1369 - 78
  9. Candela M, Maccaferri S, Turroni S, Carnevali P, Brigidi P. Functional intestinal microbiome, new frontiers in prebiotic design. Int J Food Microbiol. 2010;140(2–3):93-101
  10. Sousa T, Paterson R, Moore V, Carlsson A. The gastrointestinal microbiota as a site for the biotransformation of drugs. Int J Pharm. 2008;363:1 - 25. Epub July 2008
  11. Kusmarwati A, Heruwati ES, Utami T, Rahayu ES. Pengaruh Penambahan Pediococcus acidilactici F-11 Sebagai Kultur Starter Terhadap Kualitas Rusip Teri (Stolephorus sp.). JPB Perikanan 2011;6(1):13 - 26
  12. Sastra W. Fermentasi Rusip [Penelitian]. Bogor: IPB; 2008
  13. Yuliana N. Profil Fermentasi "Rusip" Yang Dibuat dari Ikan Teri (Stolephorus sp). Agritech. 2007;27(1):12 - 7
  14. Rosida, Rosida DF. Evaluasi Nilai Gizi Tepung Pra-Masak Pisang Tanduk dan Pisang Raja Nangka. JTIP. 2011;22(2):125 - 9
  15. Nurdin SU. Evaluasi Efek Laksatif dan Fermentabilitas Komponen Pembentuk Gel Daun Cincau Hijau (Premna oblongifolia Merr.). JTIP. 2007;18(1):10 - 6
  16. FDA. Guidance for Industry : Estimating the Maximum Safte Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers. In: (CDER) CfDEaR, editor. Rockville, USA: U.S. HHS; 2005. p. 1 - 27
  17. Corthier G, Doré J. A new era in gut research concerning interactions between microbiota and human health. Gastroen Clin Biol. 2010;34, Supplement 1(0):S1-S6
  18. Marteau P, Pochart P, Doré J, Béra-Maillet C, Bernalier A, Corthier G. Comparative study of bacterial groups within the human cecal and fecal microbiota. Appl Environm microbiol. 2001;67(10):4939-42
  19. Astawan M, Wresdiyati T, Hartanta AB. The Utilization of Seaweed as a Source of Dietary Fiber to Decrease the Serum Cholesterol in Rats. HAYATI J Biosci. 2009;12(1):23
  20. Douglas LC, Sanders ME. Probiotics and Prebiotics in Dietetics Practice. J Am Diet Assoc. 2008;108(3):510-21
  21. Montalto M, D’Onofrio F, Gallo A, Cazzato A, Gasbarrini G. Intestinal microbiota and its functions. Digest Liver Dis. 2009;3:30 - 4
  22. Mauliana D. Pengaruh Penambahan Berbagai Sumber Karbohidrat Terhadap Kadar Asam Laktat pada Fermentasi Rusip Ikan Bilis. Media Infotama. 2006;1(2):40 - 8
  23. Tiihonen K, Ouwehand AC, Rautonen N. Human intestinal microbiota and healthy ageing. Ageing Research Reviews. 2010;9(2):107-16
  24. Parameswari A, Kuntari S, Herawati. Daya hambat probiotik terhadap pertumbuhan streptococcus mutans. Surabaya: Unair; 2009
  25. Koesoemawardani D. Analisis Sensori Rusip dari Sungailiat - Bangka. JTHP 2007;12(2):36 - 9

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