DOI: https://doi.org/10.14710/jphi.v%25vi%25i.1-9

Correlation between Hematologic Parameters and Asymptomatic Bacteriuria in the Full-Term Pregnant Patients in Dr. Kariadi Hospital, Semarang, Indonesia

*Muhamad Sukri  -  Obstetrics and Gynecology Department, Diponegoro University, Indonesia, Indonesia
Open Access Copyright (c) 2022 Diponegoro International Medical Journal
Creative Commons License This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

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Abstract

Objective: We investigated the role of hematologic parameter such as hemoglobin, white blood  cells, platelet, hemoglobin platelet ratio (HPR), hemoglobin white blood cells ratio (HWR) in  full-term pregnant patients and correlate the result with their urine culture following delivery.  Methods: Between 2019-2020, a total number of 95 pregnant patients were retrospectively  evaluated at the maternal ward.

Results: The average age of the subjects was 29.15 (SD ± 5.95), median of parity of 2 (range 1- 4) and mean of gestational age was 37.5 (SD ± 1.67). There is no difference between groups on  the surgery types and comorbidities condition. Among the patients, 14 urine cultures produced  growth of 105 CFU/ml bacteria. Pearson’s correlation test showed that leukocyte inversely  correlated with bacteriuria, meanwhile hemoglobin white blood cell ratio (HWR) is positively  correlated with urinary culture result. In the diagnostic performance, HWR had AUC of 0.765  with sensitivity and specificity of 78.6% and 64.2% respectively at the cut off of 11.92.

Conclusions: Prediction of asymptomatic bacteriuria in pregnant patient by simple calculation of  HWR might be helpful in significantly reducing workload and costs of urine culture. It is a great  advantage that the parameters we use in our work are easily accessible and can be performed in  emergency conditions.

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Keywords: Asymptomatic bacteriuria, Hemoglobin white blood cells ratio, pregnant women

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Section: Original Research Article
Language : EN
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  2. Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, et al. Screening for Asymptomatic Bacteriuria in Adults: US Preventive Services Task Force Recommendation Statement. JAMA - J Am Med Assoc. 2019;322(12):1188–94
  3. Çelen Ş, Oruç AS, Karayalçin R, Saygan S, Ünlü S, Polat B, et al. Asymptomatic Bacteriuria and Antibacterial Susceptibility Patterns in an Obstetric Population. ISRN Obstet Gynecol. 2011;2011:1–4
  4. Wing DA, Fassett MJ, Getahun D. Acute pyelonephritis in pregnancy : an 18-year retrospective analysis. Am J Obstet Gynecol [Internet]. 2014;210(3):219.e1-219.e6. Available from: http://dx.doi.org/10.1016/j.ajog.2013.10.006
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  6. Gundersen TD, Krebs L, Christine E, Loekkegaard L, Rasmussen SC, Glavind J, et al. Postpartum urinary tract infection by mode of delivery : a Danish nationwide cohort study. 2018;1–9
  7. Schmiemann G, Kniehl E, Gebhardt K, Matejczyk MM, Hummers-pradier E. The Diagnosis of Urinary Tract Infection. 2010;107(21):361–8
  8. Chu CM, Lowder JL. Expert Reviews Diagnosis and treatment of urinary tract infections across age groups. Am J Obstet Gynecol [Internet]. 2018;219(1):40–51. Available from: https://doi.org/10.1016/j.ajog.2017.12.231
  9. Kim SY, Park Y, Kim H, Kim J, Koo H, Kwon C. crossm Rapid Screening of Urinary Tract Infection and Discrimination of Gram-Positive and Gram-Negative Bacteria by Automated Flow Cytometric Analysis Using Sysmex UF-5000. 2018;56(8):1–14
  10. Pieretti B, Brunati P, Pini B, Colzani C, Congedo P, Rocchi M, et al. Diagnosis of Bacteriuria and Leukocyturia by Automated Flow Cytometry Compared with Urine Culture ᰔ. 2010;48(11):3990–6
  11. Kim D, Oh SC, Liu C, Kim Y, Park Y, Jeong SH. Prediction of urine culture results by automated urinalysis with digital flow morphology analysis. Sci Rep [Internet]. 2021;(0123456789):1–8. Available from: https://doi.org/10.1038/s41598-021-85404-1
  12. Devillé WLJM, Yzermans JC, Duijn NP Van, Bezemer D, Windt DAWM Van Der, Bouter LM. of the accuracy. 2004;14:1–14
  13. Sipahi T, Köksal T, Tavil B, Akar N. The effects of acute infection on hematological parameters. Pediatr Hematol Oncol. 2004;21(6):511–8
  14. Tang W, Zhang W, Li X, Cheng J, Liu Z, Zhou Q, et al. Hematological parameters in patients with bloodstream infection: A retrospective observational study. J Infect Dev Ctries. 2020;14(11):1264–73
  15. KhalilAlaaraji K, Al-Obaidy QM, Mahdi SS. The utility of platelet indices in diagnosis of urinary tract infection. Ann Trop Med Public Heal. 2020;23(9)
  16. Gu W, Huang W, Zhang J, Qian S, Cao H, Ge L. Evaluation of urinary inflammatory index in rapid screening of urinary tract infection. Sci Rep [Internet]. 2020;10(1):1–7. Available from: https://doi.org/10.1038/s41598-020-76352-3
  17. Honda T, Uehara T, Matsumoto G, Arai S, Sugano M. Neutrophil left shift and white blood cell count as markers of bacterial infection. Clin Chim Acta [Internet]. 2016; Available from: http://dx.doi.org/10.1016/j.cca.2016.03.017
  18. Tartar AS, Balin SO. Geriatric urinary tract infections: The value of laboratory parameters in estimating the need for bacteremia and intensive care unit. Pakistan J Med Sci
  19. ;35(1):215–9
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  21. Jin BK, Baek KS, Rhie SK, Lee JH. The White Blood Cell Count to Hemoglobin Level Ratio is Correlated with the Presence of Cortical Defects on DMSA Renal Scans in Children with Febrile Urinary Tract Infection. Child Kidney Dis. 2018;22(2):42–6
  22. Churchill D, Nair M, Stanworth SJ, Knight M. The change in haemoglobin concentration between the first and third trimesters of pregnancy : a population study. 2019;0:1–6

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