DOI: https://doi.org/10.14710/baf.8.1.2023.29-35

Pengaruh Suplementasi Kurkumin dan Injeksi Hormon Tiroksin Pada Ikan Mas (Cyprinus carpio L) Terhadap Konsentrasi Hormon Tiroksin dan Laju Pertumbuhan Spesifik

Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Negeri Manado, Jl Kampus Unima, Tonsaru, Tondano Selatan, Sulawesi Utara, Indonesia, Indonesia

Open Access Copyright 2022 Buletin Anatomi dan Fisiologi

Citation Format:
Abstract

Hormon tiroksin merupakan salah satu jenis hormon tiroid yang berperan penting dalam merangsang pertumbuhan dan perkembangan gonad. Sedangkan kurkumin merupakan senyawa bioaktif yang dapat meningkatkan proses reproduksi pada ikan. Penelitian ini bertujuan untuk mengetahui profil konsentrasi hormon tiroksin dan pertumbuhan spesifik ikan uji yang diberi suplementasi kurkumin dan penyuntikan hormon tiroksin. Ikan mas betina yang digunakan dalam penelitian ini sebanyak 40 ekor. Rancangan percobaan yang digunakan adalah rancangan acak lengkap dengan faktorial 4 x 2. Faktor pertama adalah dosis kurkumin yang terdiri dari 4 konsentrasi (0; 2.5; 5; 10 g curcumin/kg feed), dan faktor kedua adalah hormon tiroksin yang terdiri dari 2 konsentrasi (0 dan 0.1 µg.g-1 bobot badan). Secara statistik data hasil penelitian menunjukkan bahwa suplementasi kurkumin dan penyuntikan hormon tiroksin berpengaruh nyata (p<0,05) terhadap konsentrasi hormon tiroksin dan laju pertumbuhan spesifik. Penelitian ini menunjukkan bahwa injeksi hormon tiroksin dan suplementasi kurkumin dapat meningkatkan konsentrasi hormon tiroksin dalam serum, dan hasil ini juga menunjukkan bahwa status reproduksi ikan uji berpengaruh terhadap peningkatan konsentrasi hormon tiroksin dan laju pertumbuhan spesifik.

 

Thyroxine hormone is one type of thyroid hormone that plays an important role in stimulating growth and gonad development. Otherwise, curcumin is a bioactive compound that can improve the process of reproduction in fish.  The aim of this study is to know the profile of the thyroxine hormone concentration and specific growth of tested fish given supplementation of curcumin and injection of thyroxine hormone. 40 female carp were used in this study. The experimental design used was a completely randomized design with a 4 x 2 factorial. The first factor was the dose of curcumin (0; 2.5; 5; 10 g curcumin/kg feed), and the second factor was thyroxine hormone (0 and 0.1 µg.g-1 body weight). Statistically, showed that the supplementation of curcumin and injection of thyroxine hormone had a significant effect (p<0.05) on the concentration of the thyroxine hormone and the specific growth rate. This study showed that the injection of the thyroxine hormone and supplementation of curcumin can increase the concentration of the thyroxine concentration in serum, and these results also showed that the reproduction status of the tested fish also influenced the increase of the thyroxine hormone concentration in serum and the specific growth rate (SGR).

Fulltext View|Download
Keywords: Kurkumin; Ikan mas; Tiroksin; laju pertumbuhan spesifik

Article Metrics:

Article Info
Section: Articles
Language : ID
Recent articles
Potensi Mangrove Avicennia Marina (Forsk.) sebagai Agen Fitoremidiasi Kadmium (Cd) di Tambak dan Laut Mangunharjo, Kecamatan Tugu, Kota Semarang UJi Kualitatif Metabolit Sekunder pada Beberapa Tanaman yang Berkhasiat sebagai Obat Tradisional Pengaruh Durasi Penggenangan Selama Fase Vegetatif Akhir Terhadap Pertumbuhan Tanaman Cabai (Capsicum frutescens L ) Varietas Sonar More recent articles
  1. Alagawany, M., Farag, M. R., Abdelnour, S. A., Dawood, M. A. O., Elnesr, S. S & Dhama, K. (2021). Curcumin and its different forms: a review on fish nutrition. Aquaculture, 532, 736030. https://doi.org/10.1016/j.aquaculture.2020.736030
  2. Brown, C. L., Urbinati, E. C., Zhang, W., Brown, S. B & McComb-kolosa, M. (2014). Maternal thyroid and glucocorticoid hormone interactions in larval fish development, and their applications in aquaculture. Reviews in Fisheries Science & Aquaculture, 22, 207–220. https://doi.org/10.1080/23308249.2014.918086
  3. Cicatiello, A. G., Girolamo, D. O & Dentice, M. (2018). Metabolic effects of the intracellular regulation of thyroid hormone: old players, new concepts. Frontiers in Endocrinology, 9. https://doi.org/10.3389/fendo2018.00474
  4. Deal, C. K & Volkoff, H. (2020). The role of the thyroid axis in fish. Frontiers in endocrinology, 11, 596585. https://doi.org/10.3389/fendo.2020.596585
  5. Dewi, C.D., Ekastuti, D.R., Sudrajat, A.O & Manalu, W. (2018). The role of turmeric powder supplementation in improving liver performance to support production of siam catfish (Pangasinodon hyppophthalmus). Omni-Akuatika, 14(1), 44–53. http://dx.doi.org/10.20884/1.oa.2018.14.1.484
  6. Habibi, H. R., Nelson, E. R & Allan, E. R. O. (2012). New insight into thyroid hormones function and modulation of reproduction in goldfish. General and Comparative Endocrinology, 175(1), 19–26. https://doi.org/10.1016/j.ygcen.2011.11.003
  7. Iromo, H., Junior, M.Z., Agus, M.S & Manalu, W. (2015). Supplementation doses thyroxine hormone of broodstock mud crab (Scylla serrate) during ovarian maturation. Journal of Aquaculture Research and Development, 6(12), 379
  8. Iromo, H., Jabarsyah, A & Awaluddin. (2018). Reproduction of females mud carb (Scylla serrata) with thyroxine hormone supplementation in traditional ponds from north borneo Indonesia. International Journal of Fisheries and Aquatic Studies, 6(3), 378–381
  9. Kasiyati., Sumiati., Ekastuti, D.R & Manalu, W. (2016). Roles of curcumin and monochromatic light in optimizing liver function to support egg yolk biosynthesis in magelang ducks. International Journal of Poultry Science, 15, 414–424. https://doi.org/10.3923/ijps.2016.414.424
  10. Liu, M., Lu, Y., Gao, P., Xie, X., Li, D., Yu, D & Yu, M. (2020). Effect of curcumin on laying performance, egg quality, endocrine hormones, and immune activity in heat-stressed hens. Poultry Science, 99(4), 2196–2202. https://doi.org/10.1016/j.psj.2019.12.001
  11. Rawung, L.D., Ekastuti, D. R., Junior, M. Z., Rahminiwati, M., Sunarma, A & Manalu, W. (2020). Reproductive performance and egg qualities in african catfish (Clarias gariepinus) broodstock supplemented with curcumin and thyroxine hormone. Omni-Akuatika, 16(1), 32–47. http://dx.doi.org/10.20884/1.oa.2020.16.1.696
  12. Rawung, L.D., Ekastuti, D. R., Junior, M. Z., Rahminiwati, M., Sunarma, A & Manalu, W. (2021a). Effectivity of curcumin and thyroxine supplementations for improving liver functions to support reproduction of African catfish (Clarias gariepinus). Jordan Journal of Biological Sciences, 14(1), 121–128
  13. Rawung, L. D., Sunarma, A & Rayer, D. J. J. (2021b). The specific growth rate (SGR) related to the histology of gonad and liver of African catfish (Clarias gariepinus) supplemented with curcumin and thyroxine hormone. Eksakta, 22(2), 154–161. https://doi.org/10.24036//eksakta/vol22-iss2/245
  14. Ruuskanen, S & Bin-Yan, H. (2018). Maternal thyroid hormones: an unexplored mechanism underlying maternal effects in ecological framework. Physiological and Biochemical Zoology, 91(3). https://doi.org/10.1086/697380
  15. Shadid, M.A., Ashraf, M.A & Sharma S. (2021). Physiology, Thyroid hormone. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK500006/
  16. Saraswati, T.R & Tana S. (2016). Effect of turmeric powder supplementation to the age of sexual maturity, physical and chemical quality of the first Japanese quail’s (Coturnix japonica) egg. Biosaintifika: Journal of Biology and Biology Education, 8(1), 18 – 24. https://doi.org/10.15294/biosaintifika.v7i2.3955
  17. Saraswati, T.R. (2015). Efek pemberian serbuk kunyit dalam pakan terhadap hepar puyuh Jepang (Coturnix japonica). Buletin Anatomi dan Fisiologi, 23(2), 94–100
  18. Yavuz, S., Del Prado, S. S. N & Celi, F. S. (2019). Thyroid hormone action and energy expenditure. Journal of the endocrine society, 3(7), 1345–1356. https://doi.org/10.1210/js.2018-00423

Last update:

No citation recorded.

Last update:

No citation recorded.