1Department of Dentistry, Faculty of Medicine, Universitas Diponegoro, Indonesia
2Department of Pathology Anatomy, Faculty of Medicine, Universitas Diponegoro, Indonesia
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@article{actodont26204, author = {Kurnia Nisa Firawan and Ira Kusuma and Hermawan Istiadi and Oedijani Santoso}, title = {The Effect of Bay Leaf Extract Gel on Increasing Fibroblasts in Traumatic Ulcers Healing Process}, journal = {Acta Odontologica Indonesia}, volume = {1}, number = {1}, year = {2025}, keywords = {}, abstract = {The wound healing process of traumatic injuries in the oral cavity involves four stage: hemostasis, inflammation, proliferation, and remodeling. Fibroblast cells are essential for the wound healing process, appearing on the 3 rd day and reaching their peak on the 7 th day after injury. This study reveals that bay leaf extract can accelerate wound healing process by mitigating inflammation and enhancing fibroblast cell activity. This research utilized a post-test only control group design. Fifteen male Wistar rats divided in 3 groups equally: control group and 2 groups were given 5% and 10% of the bay leaf extract gel was applied twice a day until the 5 th day. The results indicated that the group treated with 10% bay leaf extract gel had significantly higher value compared to the control group and the group treated with 5% bay leaf extract gel. In this study, we can learn that bay leaf extract gel can increase of fibroblast cells in the ulcer healing process.}, issn = {3090-7411}, pages = {19--24} doi = {10.14710/actodont.26204}, url = {https://ejournal2.undip.ac.id/index.php/actodont/article/view/26204} }
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