Separation of Saponin Using Nanofiltration Membrane

*Nur 'Aini Hamada  -  Membrane Research Center, Integrated Laboratory for Research and Services, Universitas Diponegoro, Indonesia
Ilham Dwiyanto Emzar  -  1. Department of Chemical Engineering, Faculty of Engineering, Diponegoro University, Indonesia
Yuniar Luthfia Listyadevi  -  1. Department of Chemical Engineering, Faculty of Engineering, Diponegoro University, Indonesia
Open Access Copyright 2021 Journal of Membranes and Materials under http://creativecommons.org/licenses/by-sa/4.0.

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Abstract
Separation of pure saponin and saponin-BSA protein mixture by nanofiltration membranes have been investigated in this study to understand the nanofiltration potential to obtain high purity saponin. Commercial NF membranes: NF, NF270, and DSS-ETNA01PP were used. The effects of the operating conditions such as pressure, the concentration of feed, and the composition of feed were evaluated. The permeate flux and rejection rate of saponin and saponin-BSA were the criteria of this evaluation. The increasing operating pressure increased the permeate flux. In addition to the membranes‘ MWCO, electrostatic repulsion between the charged membrane interface and solute determined the saponin and saponin-BSA solution's rejection rate. The flux of pure saponin feed was greater but generated lower rejection rates than the saponin-BSA feed.  Increasing feed concentration resulted in an increased rejection rate. However, the flux decreased with increasing pure saponin concentration but increased with a higher dose of saponin-BSA. The DSS-ETNA01PP membrane had the largest flux value and the smallest rejection value compared to other membranes. The results indicated that nanofiltration was potential for the saponin purifying process.
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Keywords: Electrostatic; Nanofiltration; Rejection; Repulsion
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Section: Articles
Language : EN
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