DOI: https://doi.org/10.14710/jekk.v6i1.7351

Toxoplasmosis and Cerebral Toxoplasmosis in HIV/AIDS Patients in Kariadi Hospital, Semarang

*Dauda Sanni Hassana  -  Universitas Diponegoro, Indonesia
Suharyo Hadisaputro  -  Universitas Diponegoro, Indonesia
Muchlis Achsan Udji Sofro  -  Rumah Sakit Kariadi, Indonesia
Received: 8 Mar 2020; Published: 28 Feb 2021.

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Abstract

Background: Toxoplasmosis is an infection caused by Toxoplasma gondii which affects the central nervous system resulting to a fatal situation in HIV patients especially at the advanced stage. Cerebral toxoplasmosis (CT) is the clinical presentation of toxoplasmosis in individuals with HIV/AIDS. The study was carried to describe the prevalence of toxoplasmosis and cerebral toxoplasmosis in HIV/AIDS patients attending the hospital setting used in the study.

Methods: Patients medical records were checked and analyzed for demographic characteristics as well as to determine the results of toxoplasma IgG tests for HIV/AIDS patients as well as those who had cerebral toxoplasmosis. The study was a descriptive study.

Results: Out of the 158 HIV/AIDS patients tested, 129 (81.6%) were positive for T. gondii. A 62.0% prevalence rate was recorded for the male subjects while 19.6% prevalence rate was recorded for the female subjects although there was no significant difference (X2=0.58, P > 0.05). 69.3% of the total population studied had cerebral toxoplasmosis with a prevalence rate of 74.3% and 25.3%) in male and female respectively. A higher prevalence was recorded from the age group >30years without significant difference (X2=0.74, P > 0.05).

Conclusion: More research is required to know the exact prevalence of the parasite in this group of individuals since not all the patients were tested.

 

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Keywords: Toxoplasmosis; HIV/AIDS; Cerebral Toxoplasmosis; RSUP Dr. Kariadi; Semarang

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  9. Ahmad, A.F., Ngui, R., Muhammad, A. R., Lim, Y. A., Rohela, M. 2014. Current status of parasitic infections among Pangkor Island community in Peninsular Malaysia. Trop. Biomed. 31: 836–843
  10. Soedarto. 2011. Buku Ajar Parasitologi Kedokteran. Jakarta; SagungSeto,
  11. Retmanasari A. 2015. Analisis Spatial dan Faktor Risiko Toksoplasmosis di Jawa Tengah Bagian Selatan. Tesis. Universitas Gadjah Mada, Yogyakarta
  12. Yulia, S., Sri, H., Irvan, R. and Afiono, A.P. 2015. Toxoplasma and viral antibodies among HIV patients and Inmates in Central Java, Indonesia. South East Asian J trop Med public health. 46(6)
  13. Amuta, E.U., Amali, O., Jacob, S.E. and Houmsou, R.S. 2012. Toxoplasma gondii IgG antibodies in HIV/AIDS patients attending hospitals in Makurdi metropolis, Benue state, Nigeria. Int J Med Biomed Res. 1 (3): 186-192
  14. Nissapatorn, V., Lee, C., Quek, K.F., Leong, C.L., Mahmud, R. and Abdullah, K.A. 2004. Toxoplasmosis in HIV/AIDS patients: a current situation. Jpn J Infect Dis. 57: 160-165
  15. Minoo, M., Farhad, M., Sara, J., Seyed, A., Seyed, A., Duman, S., Fatemeh, F., Hossain, J., Mahboubeh, H. 2011. Seroprevalence of Toxoplasmosis in HIV+/AIDS Patients in Iran. Acta Med Iranica. 49: 213-218

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