DOI: https://doi.org/10.14710/jekk.v9i1.14198

Profil Penggunaan Antibiotik untuk Pengobatan Pasien COVID-19 di Salah Satu Rumah Sakit Kota Bitung

*Randy Tampa'i  -  Universitas Kristen Indonesia Tomohon, Indonesia
Destine Daity Lumepaa  -  Sentra Medika Hospital Minahasa Utara, Indonesia
Devita Kristianty Johana Mangangantung  -  Sentra Medika Hospital Minahasa Utara, Indonesia
Received: 14 Oct 2023; Published: 28 Feb 2024.

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Abstract

Background: The overuse and misuse of antibiotics during the COVID-19 pandemic is one of the biggest concern that needs attention, considering antimicrobioal resistance has been a major threat to global health. According to WHO, this condition can make the infection difficult to treat, increasing the risk of disease spread and mortality. The significant increase in the number of COVID-19 cases in North Sulawesi and the excessive use of antibiotics in COVID-19 patients, shows that research that aims to describe the use of antibiotics in COVID-19 is needed as an early detection of irrational use of antibiotics.

Methods: This study was carried out in one of the COVID-19 Referral Hospital in the city of Bitung. The data of this study was collected by purposive sampling and conducted retrospectively. Sources of secondary data is from the patient medical records and patient treatment records. In this study 148 samples that meet the inclusion criteria are used. The inclusion criteria is hospitalized patients which is confirmed with COVID-19 during the period of July-December 2021, received antibiotic therapy during the treatment period, and medical record data.

Result: The result shows that the mostly used antibiotics for COVID-19 theraphy are Azithromycin tablets 47.97% from the macrolide groups; Ceftriaxone injection 20.32% and Cefixime tablets 16.67% from the cephalosporin groups;  and Levofloxacin infusion 8.94% from the fluoroquinolones group.

Conclusion : Patients at the productive age is most likely to get exposed with COVID-19. The clinical symptoms frequently occur in the mild category (68.92%). The use of antibiotics in COVID-19 patients at one of the COVID-19 Referral Hospitals in Bitung City is in accordance with the 3rd edition of the COVID-19 Management Guidelines, and the mostly used antibiotics is Azithromycin tablets as many as 118 patients (47.97%).

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Data Populasi dan Sampel Penggunaan Obat Pasien COVID-19 di Salah Satu Rumah Sakit Kota Bitung Solawesi Utara
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Keywords: Antibiotics ; Corona Virus Disease (COVID) ; Bitung City Hospital

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  8. Wasityastuti, W., Dhamarjati, A., dan Siswanto. 2019. Imunosenesens dan kerentanan populasi usia lanjut terhadap Coronavirus Disease 2019 (COVID-19). Respi. Ind. 40(3): 182–191
  9. Burhan, E., Susanto, A.D., Nasution, S.A., Eka G., Pitoyo C., et al., 2022. Cedera miokardium pada infeksi COVID-19. In Pedoman tatalaksana COVID-19 edisi 4
  10. Metlay, J.P., and Waterer GW., 2020. Treatment of community-acquired pneumonia during the pnademic. BMC. 2019: 1–3
  11. Hidayah, N., dan Haryavany, D., 2022. Efektivitas azitromisin sebagai terapi Covid-19 effectiveness of azithromycin As Therapy COVID-19. J. Pharmac. 7(1): 49–56
  12. Donsu, Y.C., dan Hasmono D., 2020. Tinjauan azitromisin pada penyakit virus korona 2019 (COVID-19). Pharmacon: J. Farm. Ind. 17(2): 133–147
  13. Jamal, J.A., Abdul-Aziz, M.H., Lipman, J., and Roberts J.A., 2013. Defining antibiotic dosing in lung infections. Clin. Pulmon. Med. 20(3): 121–128
  14. Association, A.P. 2009. Drug information Handbook 17th Edition. In Drug Information Handbook 17th Edition: Vol.17
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  17. Lisni, I., Mujianti, D., dan Anggriani, A. 2021. Profil antibiotik untuk pengobatan pasien Covid-19 di suatu Rumah Sakit di Bandung. J. Ilmiah Farmako. Bahari, 12(2): 99

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