Influence of Epidemiological Risk Factors for Occurrence of Hepatitis B Virus (HBV) Co-Infection in HIV/AIDS Patients: (Study in dr. Kariadi Hospital, Semarang, Indonesia)
Background: Chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma are all have a major cause which is Hepatitis B virus (HBV). Given the fact that HIV and HBV are all transmitted through the same routes, co-infection is common. The objective of this research is to identify several risk factors which influence the occurrence of Hepatitis B virus infection in HIV/AIDS patients at Kariadi, Semarang, Indonesia.
Method: This research is analytical observational with a case control study design, a sample of 68(34 cases and 34 controls) For all HIV patients involved in the study, samples were determined by a positive HBsAg test, The dependent variable is HBV occurrence in HIV/AIDS individuals and dependent variable were CD4≤100, Age>30,gender,marital status ,level of education ,male who have sex with other male(MSM),Analysis of data was done through univariate, bivariate and multivariate analysis with logistic regression.
Result: Variables that were proven to influence the occurrence HBV infection in HIV/AIDS individuals, after analysis were CD4≤100(p= 0.003 OR=7.535, 95% CI=(2.029-27.990 ) , being male who do sex with male( MSM) (P=0.027 ,OR=3.544 ,95%CI=( 1.158-10.848) . The probability for HIV/AIDS patients to be infected by HBVirus when they have both these risk factors is equal to 88.18%.
Conclusion: The factors that were proven to affect the influence of occurrence Hepatitis B virus in HIV/AIDS patients were, CD4≤100 and being male who do sex with other male (MSM).
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- Mohamad WMW, Ab Rahman WSW, Al-Salih SAA, Hussin CMC. Immunological and Haematological Changes in HIV Infection. Trends Basic Ther Options HIV Infect - Towar a Funct Cure. Published online 2015. doi: 10.5772/61259
- Soriano V, Vispo E, Martin-Carbonero L, Barreiro P. HCV and HIV coinfection. Curr Hepat Rep.2011;10(1):52-61. doi: 10.1007/s11901-010-0080-0
- Gedela K, Wirawan DN, Wignall FS, et al. Getting Indonesia’s HIV epidemic to zero? One size does not fit all. Int J STD AIDS. 2021;32(3):290-299. doi: 10.1177/0956462420966838
- Yano Y, Utsumi T, Lusida MI, Hayashi Y. Hepatitis B virus infection in Indonesia. World J Gastroenterol.2015;21(38):10714-10720. doi: 10.3748/wjg.v21.i38.10714
- Dakl AAA, Alnuaimy WA. Epidemiology of hepatitis B and C in Al-Muthanna province. Indian J Forensic Med Toxicol. 2020;14(2):492-494. doi: 10.37506/ijfmt.v14i2.2851
- Singh KP, Crane M, Audsley J, Avihingsanon A, Sasadeusz J, Lewin SR. HIV-Hepatitis B Virus Coinfection: Epidemiology, Pathogenesis, and Treatment. Vol 31.; 2017. doi: 10.1097/QAD.0000000000001574
- Chandra N, Joshi N, Raju YSN, Kumar A, Teja VD. Hepatitis B and/or C co-infection in HIV infected patients: A study in a tertiary care centre from south India. Indian J Med Res. 2013;138(DEC):950-954
- Adeyemi OA, Mitchell A, Shutt A, et al. Hepatitis B virus infection among men who have sex with men and transgender women living with or at risk for HIV: a cross sectional study in Abuja and Lagos, Nigeria. BMC Infect Dis. 2021;21(1):654. doi: 10.1186/s12879-021-06368-1
- Zhang X, Jia M, Chen M, et al. Prevalence and the associated risk factors of HIV, STIs and HBV among men who have sex with men in Kunming, China. Int J STD AIDS. 2017;28(11):1115-1123.doi: 10.1177/0956462416688818
- Komlos j, Landes r. Alice to the Red Queen: imperious econometrics. Econ Hist Rev.1991;44(1):133-136.doi: 10.1111/j.1468-0289.1991.tb01269.x
- Freitas SZ, Soares CC, Tanaka TSO, et al. Prevalence, risk factors and genotypes of hepatitis B infection among HIV-infected patients in the State of MS, Central Brazil. Brazilian J Infect Dis. 2014;18(5):473-480.doi: 10.1016/j.bjid.2014.01.005
- Bhattarai M, Baniya JB, Aryal N, et al. Epidemiological Profile and Risk Factors for Acquiring HBV and/or HCV in HIV-Infected Population Groups in Nepal. Biomed Res Int. 2018;2018. doi: 10.1155/2018/9241679
- Ghasemzadeh I, Roshanfekr R, Jafaripour A, Hamadiyan H. Analysis of Hepatitis B Transmission Risk Factors in HIV Patients. Int J Med Res Heal Sci. 2016;5(9):22-27. www.ijmrhs.com
- Wu S, Yan P, Yang T, Wang Z, Yan Y. Epidemiological profile and risk factors of HIV and HBV/HCV co-infection in Fujian Province, southeastern China. J Med Virol. 2017;89(3):443-449. doi: 10.1002/jmv.24666
- Senoglu S, Yesilbag Z, Karaosmanoglu HK, Aydin OA. Prevalence of HBV/HCV co-infection and associated risk factors in people living with HIV. Hepat Mon. 2020;20(4):0-5. doi: 10.5812/hepatmon.98594
- Anteneh ZA, Wondaye E, Mengesha EW. Hepatitis B virus infection and its determinants among HIV positive pregnant women: Multicenter unmatched case-control study. PLoS One. 2021;16(4 April):1-15. doi: 10.1371/journal.pone.0251084
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