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Obesity and Severity COVID-19 : Literature Review Study

*Disa Hijratul Muharramah  -  Universitas Indonesia, Indonesia
Nurhayati Prihartono  -  Universitas Indonesia, Indonesia

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Background: Coronavirus disease (COVID-19) caused by SARS-CoV 2 (Severe Acute Respiratory Syndrome) has spread worldwide and infected more than 180 million confirmed cases and 3,9 million deaths. The clinical manifestations of COVID-19 range from asymptomatic or mild infection to severe. Previous reports identified that obesity is associated with the condition of a person infected with COVID-19 develop into severe. This study aims at examining the risk of severity COVID-19 associated with obesity 

Methods: This study  was conducted a literature review method. There are ten articles obtained from online databases at Pubmed, Google Schoolar and the Wiley Online Library.

Result: The results of various studies using cohort and cross-sectional study designs show that obesity has a statistically significant association with increasing risk for the severity of COVID-19. Obese individuals infected with COVID-19 suffer severe and critical symptoms that impact patients admitted to ICU, intubation and death.

Conclusion : Obesity increase the risk for severity of COVID-19.  Maintain healthy life style, including routine exercise, choice of healthy food and routine medical checkup may reduce the risk of severity of COVID-19

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Keywords: obesity; severity; COVID-19

Article Metrics:

  1. Kalligeros, M., Shehadeh, F., Mylona, E. K., Benitez, G. & Beckwith, C. G. 2020. Association of Obesity with Disease Severity Among Patients with Coronavirus Disease 2019. 28, 1200–1204
  2. Fresan, U. & et al. 2021. Independent Role of Severe Obesity as a Risk Factor for COVID-19 Hospitalization : A Spanish Population-Based Cohort Study. Obesity 29, 29–37
  3. Wang, J. et al. 2020. Overweight and Obesity are Risk Factors of Severe Illness in Patients with COVID-19. Obesity 28, 2049–2055
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  12. Zhu, Z. et al. 2020. Association of obesity and its genetic predisposition with the risk of severe COVID-19 : Analysis of population-based cohort data. Metabolism 112, 154345
  13. Hamer, M., Gale, C. R., Kivimäki, M. & Batty, G. D. 2020. Overweight , obesity , and risk of hospitalization for COVID-19 : A community-based cohort study of adults in the United Kingdom. 25–27. doi: 10.1073/pnas.2011086117
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  15. Klang, E., Kassim, G., Soffer, S. & Freeman, R. 2020. Severe Obesity as an Independent Risk Factor for COVID-19 Mortality in Hospitalized Patients Younger than 50. 28, 1595–1599
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  17. Czernichow, S., Beeker, N., Rives-lange, C. & Guerol, E. 2020. Obesity Doubles Mortality in Patients Hospitalized for ( SARS-CoV-2 ) in Paris Hospitals , France : A Cohort Study. Obesity 28, 2282–2289
  18. Frank, R. C. et al. 2020. Obesity and the Risk of Intubation or Death inPatients With Coronavirus Disease 2019. Crit. Care Med. 1–5. doi: 10.1097/CCM.0000000000004553
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  22. Centers for Disease Control and Prevention (CDC). 2020. Overweight and Obesity
  23. Kompaniyets, L. et al. 2020. Body Mass Index and Risk for COVID-19–Related Hospitalization, Intensive Care Unit Admission, Invasive Mechanical Ventilation, and Death — United States, March–December 2020
  24. Centers for Disease Control and Prevention (CDC). 2020. Obesity, Race/Ethnicity, and COVID-19

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