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Opioid Use in Palliative Care: A Qualitative Study and Assessment of Patients’ Quality of Life at Anutapura Hospital, Palu, Indonesia.

*Rudi Safarudin orcid scopus  -  1. Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Tadulako University, Palu, Central Sulawesi, Indonesia, Indonesia
Fyolla Patricia Panto  -  1. Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Tadulako University, Palu, Central Sulawesi, Indonesia, Indonesia
Aresh Bilal  -  3. Wayne State University School of Medicine, Detroit, Michigan, USA, United States
Afriani Kusumawati  -  1. Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Tadulako University, Palu, Central Sulawesi, Indonesia, Indonesia
Ririn Hardani  -  1. Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Tadulako University, Palu, Central Sulawesi, Indonesia, Indonesia
Eny Kustiowaty  -  4. Anutapura Hospital, Palu, Central Sulawesi, Indonesia, Indonesia
Irnayanti Irnayanti  -  4. Anutapura Hospital, Palu, Central Sulawesi, Indonesia, Indonesia
Received: 1 Oct 2025; Revised: 16 Oct 2025; Accepted: 6 Nov 2025; Available online: 29 Jan 2026; Published: 29 Jan 2026.
Open Access Copyright 2026 Generics: Journal of Research in Pharmacy

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Abstract

Palliative care, being the state of care dealing with patients with terminal conditions often utilizes opioid analgesics to manage the moderate and severe pain endured by the patients. Despite their powerful painkiller, opioids are notorious for their negative consequences on several aspects of the users’ health. To investigate the knowledge, perceptions, and experiences, as well as the quality of life of patients receiving opioids in palliative care. This study is a descriptive qualitative design with a phenomenological approach. Of the 14 opioid users identified between 2023-2024 in palliative setting, with purposive sampling approach, we recruited 5 (five) eligible patients who were willing to participate in the study. We interviewed the patients using the developed questionnaire, referencing the existing published opioid qualitative literature. The eight qualitative questionnaire domains were: (1) Pain/physical ailments (2) Resources/Support system, (3) Knowledge and Awareness of The Medication, (4) Functionality, Autonomy, and Mobility, (5) Physical, Emotional, and Psychological health, (6) Coping/Resources, (7) Feeling of security in treatment, (8) Hope. Furthermore, we added patients’ clinical data from the medical records, and quality of life measured with the SF-12 questionnaire. It is worth noticing that the patients perceived inadequate information about the holistic aspects of opioid use. Regardless, the patients still found that the opioids were viable for their pain management. However, they were still somehow worried about the side effects of the drugs. In general, judging from the SF-12 measurement, the patients had good health conditions. Despite the viability of the drugs in pain management, participants' knowledge of opioids as strong analgesics could still be improved. The opioid users were also still concerned about addiction, physical dependence, and other side effects. Overall, the patients felt the opioids’ benefits, as shown by their relatively good health conditions and quality of life.

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Keywords: Central Sulawesi; Interview; Narcotics; Pain; Qualitative Study

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  1. Candrasari, K.M., Sutrisno, S., Widiyono, W., et al. (2023) ‘Management of common opioid-induced adverse effects’, Jurnal Perawat Indonesia, 7(2), pp. 975-993. Available at: https://doi.org/10.32584/jpi.v7i3.2050
  2. Coyle, M., Name, T. & Revd, R.T. et al. (2013) ‘Covariance structure analysis of health-related indicators for elderly people living at home, focusing on subjective sense of health’, Papers of Knowledge: Toward a Media History Documentation, (2), p. 6
  3. Dassieu, L., Heino, A., Develay, É., et al. (2021) ‘Conversations About Opioids: Impact of the Opioid Overdose Epidemic on Social Interactions for People Who Live With Chronic Pain’, Qualitative Health Research, 31(9), pp. 1657-1669. Available at: https://doi.org/10.1177/10497323211003063
  4. Djayanti, S., Untung, W.G.G.M., Di, L.S., Alquati, S., et al. (2022) ‘Rates and risk factors for prolonged opioid use after major surgery: Population based cohort study’, BMJ, 3(1), pp. 1-10. Available at: https://doi.org/10.1136/bmj.g1251
  5. Febby, A. M. (2023) ‘Dukungan Keluarga Berhubungan Dengan Kualitas Hidup Pasien Gagal Jantung’, Jurnal Penelitian Perawat Profesional, 5(2), pp. 691-702. Available at: https://doi.org/10.37287/jppp.v5i2.1537
  6. Haraldstad, K., Wahl, A., Andenæs, R. (2019) ‘A systematic review of quality of life research in medicine and health sciences’, Quality of Life Research, 28(10), pp. 2641–2650. Available at: https://doi.org/10.1007/s11136-019-02214-9
  7. Julianto, V., Cahayani, R.A., Sukmawati, S. and Aji, E.S.R. (2020) ‘Hubungan antara Harapan dan Harga Diri Terhadap Kebahagiaan pada Orang yang Mengalami Toxic Relationship dengan Kesehatan Psikologis’, Junal Psikologi Integratif, 8(1), p. 103. Available at: https://doi.org/10.14421/jpsi.v8i1.2016
  8. Krisdiana, H., Ayuningtyas, D., Iljas, J. and Juliati, E. (2022) ‘Hubungan Beban Kerja Tenaga Kesehatan dengan Kelelahan Kerja di Puskesmas Kecamatan Sukmajaya Kota Depok Selama Pandemi’, Jurnal Biostatik, Kependudukan, dan Informatika Kesehatan, 2(3), pp. 136-147. Available at: https://doi.org/10.51181/bikfokes.v2i3.6248
  9. Kristianti, J., Widani, N.L. and Anggreaini, L.D. (2020) ‘Pengalaman Pertama Menjalani Hemodialisa Pada Pasien Gagal Ginjal Kronik’, Jurnal Ilmiah Ilmu Keperawatan Indonesia, 10(03), pp. 65-71. Available at: https://doi.org/10.33221/jiiki.v10i03.619
  10. Lau, J., Mazzotta, P., Fazelzad, R. et al. (2021) ‘Assessment tools for problematic opioid use in palliative care: A scoping review. ‘, Palliative Medicine, 35(7), pp. 1295–1322. Available at: https://doi.org/10.1177/02692163211015567
  11. Listyarini, A.D. & Alvita, G.W. (2020) ‘Pemberdayaan kader kesehatan tentang sosialisasi palliative care "Centama" di wilayah kerja Puskesmas Gribig Kecamatan Gebog Kabupaten Kudus’, Jurnal Pengabdian Kesehatan, 3(2), pp. 123-131. Available at: https://doi.org/10.31596/jpk.v3i2.85
  12. Lukito, J.I. (2023) ‘Kombinasi analgesik non-opioid intravena untuk tata laksana nyeri akut. Cermin Dunia Kedokteran’, 50(9), pp. 509–515. Available at: https://doi.org/10.55175/cdk.v50i9.868
  13. Murda, A., Listyarini, A., Nadia, A., Nur, L.D. and Taufiqurrohman, W.N.M. (2023) ‘Literature Review: Faktor Yang Berkaitan Dengan Kejadian Congestive Heart Failure (Chf)’, Jurnal Kesehatan dan Kedokteran. 2(2), pp. 38-49. Available at: https://doi.org/10.56127/jukeke.v2i2.588
  14. Putra, O.N., Hidayatullah, A.Y.N., Aida, N. & Hidayat, F. 2022. Evaluasi kualitas hidup pasien tuberkulosis paru menggunakan instrumen Short Form-36. Jurnal Ilmiah Farmasi Bahari, 13(1), pp. 1. Available at: https://doi.org/10.52434/jfb.v13i1.1398
  15. Rafli, R., Zulfiqar, Y., Hanum, F.J., Muspita, V., Murni, A.W. and Antonius, P.A. (2023) ‘Peningkatan Peran Caregiver dalam Support System untuk Pasien Kanker’, Jurnal Kreativitas Pengabdian Kepada Masyarakat, 6(3), pp. 853-863. Available at: https://doi.org/10.33024/jkpm.v6i3.8512
  16. Romero E. (2019) ‘12-item short form survey (SF-12)’. Available at: https://www-physio--pedia-com.translate.goog/12-Item_Short_Form_Survey_(SF-12)?_x_tr_sl=en&_x_tr_tl=id&_x_tr_hl=id&_x_tr_pto=tc#References
  17. Sampelan, N.S. (2023) ‘Hubungan Self Care dan Dukungan Keluarga dengan Kualitas Hidup pada Pasien Gagal Jantung Kongestif di RSD dr. dr. H. Soemarno Sosroatmodjo’, SAINTEKES Jurnal Sains, Teknologi Dan Kesehatan, 2(2), pp. 213-224. Available at: https://doi.org/10.55681/saintekes.v2i2.76
  18. Sari, D., Sudadi & Hanafi, I. (2019) ‘Pemberian opioid sebagai manajemen nyeri pada pasien pediatrik’, Jurnal Komplikasi Anestesi, 6(3), pp. 85–94
  19. Susanto, D. (2020) ‘Mencermati Pelayanan Penyembuhan Pada Masa Kini’, The New Perspective in Theology and Religious Studies, 1(1), pp. 1-18. Available at: https://doi.org/10.47900/nptrs.v1i1.4
  20. Witarini, N.W.S., Agustini, N.L.P.I.B. & Sriasih, N.K. (2023) ‘Perbedaan pengetahuan dan sikap mahasiswa keperawatan tentang perawatan paliatif pada anak dengan kanker dan non kanker di Denpasar’, Journal Center of Research Public Health Midwifery and Nursing, 7(2), pp. 49-59. Available at: https://doi.org/10.36474/caring.v7i2.300
  21. Yulianti, Y., Tresnawan, T., Purnairawan, Y., & Oktavia, A. (2023). Identification Of Factors Affecting The Quality Of Life In Hypertension Patients. HealthCare Nursing Journal, 5(2) 711-721
  22. Yun Jufan, A., Kurniawaty, J., Dewi, D.R. et al. (2021) ‘Terapi opioid pada kasus COVID-19. Jurnal Komplikasi Anestesi’, 9(1)

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