DOI: https://doi.org/10.14710/dimj.v4i1.15837

Electrocardiographic Pattern of Pregnant Women with Advanced Maternal Age

*Arjatya Pramadita Mangkoesoebroto  -  Department of Cardiology and Vascular Medicine, Faculty of Medicine Diponegoro University – Kariadi General Hospital, Semarang, Indonesia, Indonesia
Besari Adi Pramono  -  Department of Obstetric and Gynecology, Faculty of Medicine Diponegoro University – Kariadi General Hospital, Semarang, Indonesia, Indonesia
Aruman Yudanto Ariwibowo Binarso Mochtar  -  Department of Cardiology and Vascular Medicine, Faculty of Medicine Diponegoro University – Kariadi General Hospital, Semarang, Indonesia, Indonesia
Open Access Copyright (c) 2023 Diponegoro International Medical Journal
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Abstract

Background: Advanced maternal age (AMA) is becoming increasingly common and is associated with increased maternal and fetal morbidity and mortality. Around 22,2% of maternal deaths were found to be from cardiovascular disease, and women with higher cardiovascular mortality were likely older. Electrocardiography (ECG) is a simple tool for detecting cardiovascular problems. Though there are many studies of the ECG in normal pregnant women, there is still limited data on the ECG pattern in pregnant women with AMA.

Objective: Describe the characteristics of the ECG pattern in woman with AMA.

Methods: This study used data retrospectively from medical records of patient in Kariadi General Hospital Semarang from 1st to 30th October 2018. The inclusion criteria were advanced age ³ 35 years,  in the last trimester. Demography, clinical, laboratory , and 12-lead ECG data were collected and reported.

Results: Thirteen patients were obtained, with mean age of 38,3 years. Majority of patients had preeclampsia (61,5%) and superimposed preeclampsia (15,4%). Mean systolic blood pressure was 168 mmHg. All of the patients was sinus rhythm, with a mean heart rate 92,5 bpm. Mean QTc was 430,7ms, with 3 patients (23,1%) having borderline prolongation grade. Another abnormality was a left atrial abnormality in 3 patients (23,1%), poor R wave progression in 2 patients (15,4%), and a pathological Q wave in 1 patients (7,7%).

Conclusion: ECG abnormalities are seen in 38,4% of pregnant women over 35 years old. The performance of an ECG in AMA may be a first step toward improved pregnancy outcomes since it is widely available and easily interpreted by general practitioners.

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Keywords: electrocardiography; advanced maternal age; cardiovascular

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Section: Original Research Article
Language : EN
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  1. Lean SC, Derricott H, Jones RL, Heazell AEP. Advanced maternal age and adverse pregnancy outcomes: A systematic review and meta-analysis. PLoS One 2017; 12: 1–15
  2. Martin JA, Hamilton BE, Sutton PD, Ventura SJ MF. Births: final data for 2006. Natl Vital Stat Rep 2009; 57: 1–102
  3. ONS. Birth Summary Tables,England and Wales,2013. Off Nartional Stat
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  5. Zhao, X. Q., Wang, C. G., Song, Y. X., & Jiao H. The relationship of ECG and pregnancy outcome of older pregnant woman in late pregnancy. Chinese J Appl Physiol 2014; 30(1): 44–47
  6. Department of Public Health Maternal Mortality Review Committee Working Group. Maternal Cardiovascular Mortality in Illinois, 2002-2011. Obstet Gynecol 2017; 129: 819–826
  7. Aslan MM, Atici A. Assessment of increased risk of arrhythmia in advanced age pregnancies. Pakistan J Med Sci 2018; 34: 687–690
  8. Baltazar RF. Basic and bedside electrocardiography. Baltimore: Lippincott Williams & Wilkins, 2009
  9. Sokolow M, Lyon T. The ventricular complex in left ventricular hypertrophy as obtained by unipolar precordial and limb leads. Am Hear J 1949; 37: 161–186
  10. H B. An analysis of the time-relations of electrocardiograms. Heart 1920; 7: 353–370
  11. Munuswamy K, Alpert MA, Martin RH, Whiting RB MN. Sensitivity and specificity of commonly used electrocardiographic criteria for left atrial enlargement determined by M-mode echocardiography. Am J Cardiol 1984; 53: 829–832
  12. Straus SMJM, Kors JA, De Bruin ML, Van Der Hooft CS, Hofman A, Heeringa J, et al. Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol 2006; 47: 362–367
  13. Schröder LC, Holkeri A, Eranti A, Haukilahti MAE, Kerola T, Kenttä T V., et al. Poor R-wave progression as a predictor of sudden cardiac death in the general population and subjects with coronary artery disease. Hear Rhythm 2022; 19: 952–959
  14. Braschi A, Abrignani MG, Francavilla VC, Abrignani V, Francavilla G. Age- and sex-based reference ranges for non-invasive ventricular repolarisation parameters. Int J Clin Pract 2017; 71: 1–9
  15. Raffaelli R, Prioli MA ntoni., Parissone F, Prati D, Carli M, Bergamini C, et al. Pre-eclampsia: evidence of altered ventricular repolarization by standard ECG parameters and QT dispersion. Hypertens Res 2014; 37: 984–988
  16. Inci S, Nar G, Aksan G, Sipahioʇlu H, Soylu K, Dogan A. P-wave dispersion and atrial electromechanical delay in patients with preeclampsia. Med Princ Pract 2015; 24: 515–521
  17. Angeli F, Angeli E, Verdecchia P. Electrocardiographic changes in hypertensive disorders of pregnancy. Hypertens Res 2014; 37: 973–975
  18. Desai D, S. MP. Electrocardiographic profile of patients with hypertensive disorders in pregnancy. Int J Reprod Contraception, Obstet Gynecol 2017; 6: 2569

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