Evolution of Maternal Care-Associated Infections at Bogdogo University Hospital in Burkina Faso

Félicité Wendin-Manegdé Nana; Absatou BA; Abdoulaye SO; Adama Ouattara; Ghislain G Poda; Charlemagne Ouedraogo; Maxime Koine Drabo

doi:10.14710/jphtcr.v8i2.26880

DOI: https://doi.org/10.14710/jphtcr.v8i2.26880

Evolution of Maternal Care-Associated Infections at Bogdogo University Hospital in Burkina Faso

Félicité Wendin-Manegdé Nana¹

, Absatou BA², Abdoulaye SO¹, Adama Ouattara², Ghislain G Poda³, Charlemagne Ouedraogo², Maxime Koine Drabo¹

¹Institute for Research in Health Sciences, CNRST, Ouagadougou, Burkina Faso

²Bogdogo University Hospital, Ministry of Health, Ouagadougou, Burkina Faso

³World Health Organization, Bangui, Central African Republic

Received: 6 May 2025; Published: 31 Aug 2025.

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

BibTex Citation Data :

@article{JPHTCR26880,
    author = {Félicité Nana and Absatou BA and Abdoulaye SO and Adama Ouattara and Ghislain Poda and Charlemagne Ouedraogo and Maxime Drabo},
    title = {Evolution of Maternal Care-Associated Infections at Bogdogo University Hospital in Burkina Faso},
    journal = {Journal of Public Health for Tropical and Coastal Region},
  volume = {8},
    number = {2},
    year = {2025},
    keywords = {Healthcare-associated infections; antimicrobial resistance; obstetrics},
    abstract = {   Introduction :   Healthcare-associated infections (HAIs) are major public health issues in healthcare facilities. It is one of the main causes of maternal mortality, particularly in developing countries, where infrastructure and infection control measures are often inadequate. This study aimed to determine the prevalence, most common infections, and responsible pathogens and antimicrobial resistance patterns of maternal HAIs in a healthcare facility in Burkina Faso.      Methods :   This retrospective cross-sectional study was based on the patients' medical records between 1 and 30 March 2025. Data from patients who developed HAIs between 2018 and 2022 were collected, with a focus on endometritis, surgical site and urinary tract infections. The causative organisms were identified, and their resistance to antimicrobials was tested. Total sampling technique was used, based on available data. Trends and factors influencing the prevalence of HAIs were also analyzed.     Results :   The overall prevalence of HAIs was 4.27%. The most common infections were endometritis (2.17%), urinary tract infections (1,36%), and surgical site infections (0.74%). The main pathogens identified were   Enterobacteriaceae   (43.3%), yeasts of the   Candida   genus (30.8%), and   staphylococci   (11%). Antimicrobial resistance was high, particularly multidrug resistance, in E. coli and K. pneumoniae strains, as well as a notable rate of methicillin-resistant Staphylococcus aureus (MRSA) at 19.04%.      Conclusion :   The prevalence of HAIs is high, and multidrug-resistant pathogens are a major complication. There is an urgent need to strengthen infection prevention strategies, improve microbiological surveillance, and promote rational use of antibiotics to control the spread of resistance.  },
   issn = {2597-4378},   pages = {111--120}  doi = {10.14710/jphtcr.v8i2.26880},
    url = {https://ejournal2.undip.ac.id/index.php/jphtr/article/view/26880}
}

Citation Format:

Abstract

Introduction: Healthcare-associated infections (HAIs) are major public health issues in healthcare facilities. It is one of the main causes of maternal mortality, particularly in developing countries, where infrastructure and infection control measures are often inadequate. This study aimed to determine the prevalence, most common infections, and responsible pathogens and antimicrobial resistance patterns of maternal HAIs in a healthcare facility in Burkina Faso.

Methods: This retrospective cross-sectional study was based on the patients' medical records between 1 and 30 March 2025. Data from patients who developed HAIs between 2018 and 2022 were collected, with a focus on endometritis, surgical site and urinary tract infections. The causative organisms were identified, and their resistance to antimicrobials was tested. Total sampling technique was used, based on available data. Trends and factors influencing the prevalence of HAIs were also analyzed.

Results: The overall prevalence of HAIs was 4.27%. The most common infections were endometritis (2.17%), urinary tract infections (1,36%), and surgical site infections (0.74%). The main pathogens identified were Enterobacteriaceae (43.3%), yeasts of the Candida genus (30.8%), and staphylococci (11%). Antimicrobial resistance was high, particularly multidrug resistance, in E. coli and K. pneumoniae strains, as well as a notable rate of methicillin-resistant Staphylococcus aureus (MRSA) at 19.04%.

Conclusion: The prevalence of HAIs is high, and multidrug-resistant pathogens are a major complication. There is an urgent need to strengthen infection prevention strategies, improve microbiological surveillance, and promote rational use of antibiotics to control the spread of resistance.

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Keywords: Healthcare-associated infections; antimicrobial resistance; obstetrics

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In Vol 8, No 2 (2025): Journal of Public Health for Tropical and Coastal Region

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Afle FCD, Quenum KJM, Hessou S, Johnson RC. Overview of healthcare-associated infections in two public hospitals in southern Benin. J Appl Biosci. 2017;118:11852–60
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Ministry of Health of Burkina Faso. Project of Prevention of Infectious Risk and Safety in Healthcare Settings (PRISMS). Ouagadougou, Ministry of Health. 2019
European Centre for Disease Prevention and Control. Healthcare-associated infections: point prevalence survey of healthcare-associated infections and antimicrobial use in European acute care hospitals 2016–2017. ECDC
Magill SS, O'Leary E, Janelle SJ, et al. Changes in prevalence of health care–associated infections in U.S. hospitals. N Engl J Med. 2018;379(18):1732-1744
Ojerinde A, Salami A, Okoro F. Prevalence, risk factors, and antimicrobial resistance of endemic healthcare-associated infections in Africa: a systematic review and meta-analysis. BMC Infect Dis. 2024;24(1):1-13
Nejad SB, Allegranzi B, Syed SB, Ellis B, Pittet D. Health-care-associated infection in Africa: a systematic review. Lancet Infect Dis. 2011;11(11):649-56
Jacques S, Laurent O, Moussiliou NP, Paul A, Alphonse K, René D, Esther T. Epidémiologie et prise en charge des infections du per-partum à la maternité du centre hospitalier départemental de l'Ouémé-Plateau au Bénin. Pan Afr Med J. 2014 Feb 4;17:89
Nkosi Z, Mkhize M, Khumalo P. Healthcare-associated infections in South African hospitals: A prevalence study. S Afr Med J. 2020;110(5):370-375
Ojerinde A, Salami A, Okoro F. Healthcare-associated infections in Africa: a systematic review and meta-analysis of point prevalence studies. J Pharm Policy Pract. 2022;15(1):1-10
Louzas I. Comment la sage-femme peut-elle contribuer à la prévention des infections nosocomiales en Gynécologie Obstétrique? Deuxième partie. Les Dossiers de l'Obstétrique. 2004;2(324):18-23
Seaward PGR, Hannah ME, Myhr TL, Farine D, Ohlsson A, Wang EE, et al. International multicenter term PROM study: evaluation of predictors of neonatal infection in infants born to patients with premature rupture of membranes at term. Am J Obstet Gynecol. 1998;179(3):635-9
Mbutshu Lukuke H. Profil épidémiologique et écologique des surfaces hospitalières et des infections nosocomiales urinaires et des sites opératoires dans les maternités des hôpitaux publics de Lubumbashi; thèse de Doctorat en Santé Publique. Inédit, ESP, Université de Lubumbashi. 2017
Merzougui L, Marwen N, Hannachi H, Asma M, Olfa BE, Waddah M, et al. Incidence et facteurs de risque de l’infection du site opératoire après césarienne dans une maternité de Tunisie. Santé publique. 2018;30(3):339-344
Koek M, Wille J, Isken M, Voss A, Van Benthem B. Post-discharge surveillance (PDS) for surgical site infections: a good method is more important than a long duration. Euro Surveill. 2015;20(8):21042
Ward VP, Charlett A, Fagan J, Crawshaw SC. Enhanced surgical site infection surveillance following caesarean section: experience of a multicentre collaborative post-discharge system. J Hosp Infect. 2008;70(2):166-73
Okeke I, Adeniran A, Bamidele M. Prevalence of healthcare-associated infections in a Nigerian teaching hospital. Afr J Clin Exp Microbiol. 2018;19(2):123-129
Lamy C, Zuily S, Perdriolle E, et al. Les infections génitales hautes: prise en charge des infections du post-partum. J Gynecol Obstet Biol Reprod (Paris). 2012;41(8):886–903
Larabi K, Masmoudi A, Fendri C. Étude bactériologique et phénotypes de résistance des germes responsables d’infections urinaires dans un CHU de Tunis : à propos de 1930 cas. Médecine et maladies infectieuses. 2003;33:348–352
Ministère de la santé et de l’hygiene publique, Rapport de la surveillance de la résistance aux antimicrobiens au laboratoire 2023. MSHP, 2024
Alvarez C, Pangon B, Allouch PY, Ghnassia JC. Infections urinaires : principaux aspects épidémiologiques, bactériologiques et cliniques. Feuillets Biol. 1992;23(no 189):15–24
Le Minor L, Veron M, editors. Bactériologie Médicale. Paris: Flammarion; 1989
Berthé B, Traoré SO, Konaté I, et al. Etude comparative des infections du site opératoire: césarienne systématique versus césarienne itérative au centre de santé de référence de la commune V du district de Bamako/Malin. Rev Mali Infect Microbiol. 2019;14:27
Hodonou Montcho Adrien. Aspects bactériologiques des infections du site opératoire au Centre Hospitalier Départemental Du Borgou à Parakou (Benin). Eur Sci J. 2016;12(9):1-10
Lepelletier D. Impact du dépistage et de la décontamination sur la prévention des infections du site opératoire à Staphylococcus aureus. Journal des Anti-infectieux. 2011;13(4):209-216
Legeay C, Hilliquin D, Brunet M, Zahar JR. Extended-spectrum beta-lactamases, what is the risk in pediatric oncology. Rev Oncol Hematol Pediatr. 2016;4(1):25-34
Traore R, et al. Antimicrobial resistance in staphylococcus aureus isolates from inpatients and outpatients in Ouagadougou, Burkina Faso. Int J Adv Res. 2020
Ouedraogo AS, et al. Emergence and spread of antibiotic resistance in West Africa: contributing factors and threat assessment. Med Sante Trop. 2017
Ling ML, Apisarnthanarak A, Madriaga G. The burden of healthcare-associated infections in Southeast Asia: a systematic literature review and meta-analysis. Clin Infect Dis. 2015;60(11):1690-1699
WHO. Core components for effective infection prevention and control programmes: new WHO evidence-based recommendations. Antimicrob Resist Infect Control. 2017;6(1):1-8
Ojerinde A, Salami A, Okoro F. Superbugs 'could kill 39m people by 2050' amid rising drug resistance. The Guardian. 2024. Available from: https://www.theguardian.com/global-development/2024/sep/16/health-superbugs-antimicrobial-resistance-amr-39m-deaths-infections-bacteria-gram-study

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