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Faktor yang Berhubungan dengan Viral Load Pada ODHIV yang Menjalani Terapi Antiretroviral (ART) di Kota Kendari: Case-Control Study

*Ni'mahtu Saleha  -  Program Studi Kesehatan Masyarakat, Fakultas Kesehatan Masyarakat, Universitas Halu Oleo, Kendari, Indonesia
La Ode Muhamad Sety  -  Program Studi Kesehatan Masyarakat, Fakultas Kesehatan Masyarakat, Universitas Halu Oleo, Kendari, Indonesia
Irma Yunawati  -  Program Studi Gizi, Fakultas Kesehatan Masyarakat, Universitas Halu Oleo, Kendari, Indonesia
Received: 15 Feb 2026; Revised: 16 May 2026; Accepted: 16 May 2026; Published: 19 May 2026.

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Abstract

Background: HIV is a global health issue, including in Indonesia and Kendari City. According to a report by the City Health Office Kota Kendari, in 2021, the prevalence of HIV was estimated to have reached 0.030% (108 cases), in 2022, it was 0.081% (290 cases), and in 2023, it reached 0.088% (321 cases). In Kendari City as of July 2025, the RSUD Kota Kendari recorded the highest number of positive HIV cases, totaling 981 cases, with 221 deaths.

Methods: This quantitative study uses a case-control design with purposive sampling and non-matching techniques, involving 112 samples, namely 56 cases (PLHIV with detectable viral load) and 56 controls (PLHIV with undetectable viral load). Considering the comfort and privacy of people living with HIV, as well as the availability of samples, two data collection methods were used: offline and online data collection. The instruments used in this study were physical questionnaires and Google Forms monitored by the PLHIV person in charge. The analyses used in this study were univariate and bivariate analyses employing the chi-square test.

Result: The results of the statistical test showed that sleep quality (OR = 0.797, CI = 0.372 – 1.710), physical activity (OR = 1.344, CI = 0.632 - 2.860), and stress levels (OR = 0.296, CI = 0.076 - 1.157).

Conclusion : In this study, sleep quality, physical activity, and stress level were not significantly associated with viral load among PLHIV receiving ART.

Note: This article has supplementary file(s).

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Keywords: Viral load; Sleep quality; Physical activity; Stress levels; PLHIV

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  1. Hoӏifah K, Tutik Sri Hariyati R, Faradita Aryani D. Mobiӏe Heaӏth Voӏuntary Counseӏing and Testing untuk Pencegahan HIV-AIDS: Literature Review. J Nurs Care. 2023;6(1):87–94
  2. Kementerian Kesehatan Republik Indonesia. Peraturan Menteri Kesehatan Republik Indonesia Nomor 23 Tahun 2022 Tentang Penanggulangan Human Immunodeficiency Virus, Acquired Immunodeficiency Syndrome, Dan Infeksi Menular Seksual. In: Peraturan Menteri Kesehatan Republik Indonesia [Internet]. 2022. p. 1–53. Available from: https://www.bing.com/search?pglt=41&q=peraturan+menteri+kesehatan+republik+indonesia+nomor+23+tahun+2022+tentang+penanggulangan+human+immunodeficiency+virus%2C+acquired+immuno+deficiency+syndrome%2C+dan+infeksi+menular+seksual&cvid=74754ff9ec074257a166a6
  3. World Health Organization. HIV and AIDS. www.who.int. 2024. p. 1
  4. Sistem Informasi HIV-AIDS dan IMS (SIHA). Laporan Eksekutif Perkembangan HIV AIDS Dan Penyakit Infeksi Menular Seksual (PIMS) Triwulan I Tahun 2023 [Internet]. Sistem Informasi HIV-AIDS dan IMS. Jakarta: Kementerian Kesehatan RI; 2023. p. 1–15. Available from: https://siha.kemkes.go.id/
  5. Dinas Kesehatan Provinsi Sulawesi Tenggara. Profil Kesehatan Provinsi Sulawesi Tenggara. Kendari; 2024
  6. Dinas Kesehatan Kota Kendari. Profil Kesehatan Kota Kendari. Kendari; 2024
  7. Kementerian Kesehatan Republik Indonesia. Cegah HIV-AIDS, Kemenkes Perluas Akses Pencegahan Pada Perempuan, Anak dan Remaja [Internet]. kemkes.go.id. 2022. p. 1. Available from: https://sehatnegeriku.kemkes.go.id/baca/umum/20221129/5041895/cegah-hiv-aids-kemenkes-perluas-akses-pencegahan-pada-perempuan-anak-dan-remaja/
  8. Antoxida VV, Pertiwi D, Milla MN. Hubungan Jumlah Total Limfosit dengan Viral Load Studi Observasional Analitik pada Penderita Terinfeksi HIV/AIDS yang Mendapat Terapi Zidovudine. Konstelasi llmiah Mhs Unissula 5 [Internet]. 2021;038:165–71. Available from: http://repository.unissula.ac.id/21054/
  9. Kementerian Kesehatan Republik Indonesia. Pemeriksaan Viral Load pada Infeksi HIV [Internet]. keslan.kemkes.go.id. 2022. p. 1. Available from: https://keslan.kemkes.go.id/view_artikel/1900/pemeriksaan-viral-load-pada-infeksi-hiv
  10. Keputusan Menteri Kesehatan Republik Indonesia. Keputusan Menteri Kesehatan Republik Indonesia Nomor HK.01.07/MENKES/90/2019 Tentang Pedoman Nasional Pelayanan Kedokteran Tata Laksana HIV. In: Keputusan Menteri Kesehatan Republik Indonesia. Jakarta: Menteri Kesehatan Republik Indonesia; 2019. p. 1–23
  11. Freeman R, Gwadz M, Francis K, Hoffeld E. Forgetting to take HIV antiretroviral therapy: a qualitative exploration of medication adherence in the third decade of the HIV epidemic in the United States. Sahara J. 2021;18(1):113–30
  12. Kurniawan F, Djauzi S, Yunihastuti E, Nugroho P. Predictors of Virological Failure in HIV Patients Receiving First Line Antiretroviral Therapy with Good Adherence. J Penyakit Dalam Indones. 2017;4(1):29–34
  13. Billjudika RR, Sawitri AAS. Prediktor Immunological Failure Pada Populasi Umum Pasien Hiv/Aids Di Kabupaten Badung, Bali: Studi Kohort Retrospektif. Med Udayana [Internet]. 2019;8(7):2019. Available from: https://ojs.unud.ac.id/index.php/eum
  14. Kementerian Kesehatan Republik Indonesia. Upaya Meningkatkan Sistem Imunitas Tubuh [Internet]. kemenkes.go.id. 2024. p. 1. Available from: https://keslan.kemkes.go.id/view_artikel/3249/upaya-meningkatkan-sistem-imunitas-tubuh
  15. Hamzah MS, Esfandiari F, Anggraini M, Kusmana A, Elta S. Pengaruh kepatuhan terapi ARV dengan rata-rata kadar viral load pada ODHIV. J Med Malahayat. 2020;6:5367–75
  16. Thamrin HY, Rahim E, Nelini. Hubungan Kepatuhan Minum Obat Dengan Viral Load Pasien HIV di Rumah Sakit Umum Daerah Kota Kendari. J Ilm Mhs Kesehat Masy. 2023;8(4):227–33
  17. Arifa MPN, Tursinawati Y, Wahab Z. Hubungan Kepatuhan Meminum Obat Antiretroviral Dengan Kadar Viral Load Pada Penderita HIV. Pros Semin Nas UNIMUS. 2022;5:1490–7
  18. World Health Organization. The role of HIV viral suppression in improving individual health and reducing transmission: policy brief. Geneva: World Health Organization; 2023. Wolrd Health Organization. 2023. 16 p
  19. Pulo EOS, Jober NF, Mnedrofa HK. Hubungan Tingkat Kelelahan Dengan Kualitas Tidur Pada Pasien HIV/AIDS di Rsud Jayapura. J Innov Res Knowl. 2026;5(10):11349–57
  20. Adillah ML, Yona S, Edison C. The relationship between quality of sleep and physical activity with level of symptom severity post-COVID-19 among HIV / AIDS patients. Eur Rev Med Pharmacol Sci. 2024;(28):2955–9
  21. Broto GW. Metode Story Telling dan Role Play untuk Reduksi Stress ADHA Story Telling and Role Play Methods for ADHA Stress Reduction Germino Wahyu Broto. Happiness; Univ Islam Negeri Tulungagung. 2024;8(June):64–83
  22. Balthazar MS, Webel A, Gary F, Burant CJ, Totten VY, Voss JG. Sleep and immune function among people living with human immunodeficiency virus (HIV). AIDS Care - Psychol Socio-Medical Asp AIDS/HIV. 2021;33(9):1196–200
  23. Farradika Y, Umniyatun Y, Nurmansyah MI, Jannah M. The Behavior of Physical Activity and Determinants of Student at Faculty Health Science, University of Muhammadiyah Prof. Dr. Hamka. Arsip Kesehat Masy. 2019;4(1):134–42
  24. Susri W, Maulina N, Nadira S. Hubungan Pekerjaan, Jenis Kelamin, Umur dan Aktivitas Fisik dengan Massa Otot pada Masyarakat Lhokseumawe. Vitalitas Medis J Kesehat dan Kedokt. 2025;2:56–67
  25. Sofro MAU, Raharja T, Hadiati T, Sari LK, Jusup I. Proporsi Gejala Depresi dan Hubungannya dengan Terapi ARV: Studi di Poliklinik VCT RSUP Dr. Kariadi. J Penyakit Dalam Indones. 2022;9(2):94

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