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Peningkatan Risiko Prematuritas Pada Ibu Hamil Penderita Covid – 19 di Kabupaten Pringsewu Lampung

*Arien Delfi Lazendra  -  Program Studi Magister Epidemiologi, Fakultas Kesehatan Masyarakat, Universitas Diponegoro Semarang 50275, Indonesia
Martha Irene Kartasurya  -  Departemen Gizi Kesehatan Masyarakat, Fakultas Kesehatan Masyarakat, Universitas Diponegoro 50275, Indonesia
Suhartono Suhartono  -  Departemen Kesehatan Lingkungan, Fakultas Kesehatan Masyarakat, Universitas Diponegoro, Semarang 50275, Indonesia
Received: 23 Sep 2023; Revised: 28 May 2025; Accepted: 28 May 2025; Published: 28 May 2025.

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Abstract

BackgroundResearch on pregnant women with COVID-19 has shown an increased risk of preterm birth, raising significant concerns in maternal health due to prematurity being a leading cause of neonatal illness and death. These findings highlight the need for further investigation, particularly in primary health care settings, to better understand the impact of COVID-19 on pregnancy. This study focuses on analyzing the heightened risk of prematurity in pregnant women infected with COVID-19.

Methods: This descriptive observational study with a case-control approach was conducted at the Pringsewu District Health Center, Lampung, from January-February 2023. A total of 180 samples were selected using the Lemeshow formula and divided into exposed and unexposed groups. Data were collected through questionnaires, medical records, pregnancy cohort books, and maternal and child health books. Analysis included univariate frequency distribution, bivariate chi-square test, and multivariate logistic regression methods.

Results : Pregnant women who were infected with COVID-19 had a 2.27 times increased risk of preterm birth (OR = 2.27; 95% CI = 1.19-4.33) compared to those who were not infected. After controlling for <4 antenatal visits and underweight gain, pregnant women with a history of COVID-19 infection still had a 2.21 times higher risk of prematurity compared to uninfected pregnant women

Conclusion : There is an increased risk of delivering premature births in pregnant women who are infected with COVID 19, even after controlling for the factors of antenatal care and weight gain during pregnancy.

Keywords : Antenatal Care; COVID 19; Pregnancy; Premature.

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