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*Anna Mailasari Kusuma Dewi  -  Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Diponegoro University Semarang, Indonesia, Indonesia
Ismiar Astika  -  Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Diponegoro University Semarang, Indonesia, Indonesia
Farokah Farokah  -  Department of Otorhinolaryngology-Head and Neck Surgery, Kariadi Hospital, Semarang, Indonesia, Indonesia
kanti yunika  -  Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Diponegoro University Semarang, Indonesia, Indonesia
Dwi Marliyawati  -  Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Diponegoro University Semarang, Indonesia, Indonesia
Open Access Copyright (c) 2023 Diponegoro International Medical Journal
Creative Commons License This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

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Background: COVID-19 can make smell and taste disorder due to Angitensin Converting Enzyme 2 (ACE2) binding to olfactory tractus and taste bud that affected by gender, age, comorbid and COVID-19 severerity.

Aim: To analyze age, gender, comorbid and COVID-19 severity as risk factor for smell and or taste disorder in mild and moderate Covid -19 patient in Semarang

Methods: Observational research used cross section design. Sample is COVID-19 patients age >10 years old with severity mild and moderate nonhospitalize that record on Health Center of Semarang City June – July 2021. Sampling metode using purposive sampling with secondary data. Association between variable analyze using Chi square or Fisher exact test, multivariate analyze with logistic regression.

Results: Research on 4337 people, 2.0% smell disorder and 0.5% taste disorder. Prevalence COVID-19 mostly on women 50.5% and adult (20-60 years old) 82.5%. Risk factor gender, age and COVID-19 severity is not associated with smell and taste disorder on COVID-19 patients (p<0.05). Chronic liver disease as a risk factor only for smell disorder on COVID-19 patients (p 0.04, CI 3.029-786.993, RP 48.828). 

Conclusion: Chronic liver disease is a comorbid as a risk factor for smell disorder ini COVID-19 patients at Semarang. age, gender and other comorbid not as a risk factor for smell and or taste disorder.


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Keywords: smell disorder, taste disorder, COVID-19
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