Copper Ferrite Superparamagnetic Nanoparticle-Catalyzed Cross-coupling Reaction to Form Diindolylmethane (DIM): Effect of Experimental Parameters

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Superparamagnetic copper ferrite (CuFe2O4) nanoparticles were utilized as a heterogenous catalyst for the cross-coupling reaction of indole to form 3,3’-diindolylmethane (DIM) as the desirable product. High reaction yield, at around 82%, was achieved under optimal conditions. The CuFe2O4 material could be easily separated from the reaction mixture by an external magnetic field and could be reutilized several times without a significant decrease in catalytic activity. We also showed that no sites of catalyst material leached into reaction solution was detected. To our best knowledge, the above cross-coupling reaction was not previously conducted under catalysis of superparamagnetic nanoparticles. Copyright © 2020 BCREC Group. All rights reserved
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Last update: 2021-01-24 17:21:16
Last update: 2021-01-24 17:21:16
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