Kinetic and Mechanistic Aspects for Oxidation of Ciprofloxacin by Soluble Colloidal Manganese Dioxide

Gajala Tazwar orcid  -  Department of Chemistry, Janki Devi Bajaj Government Girls College, India
*Vijay Devra orcid  -  Department of Chemistry, Janki Devi Bajaj Government Girls College, India
Received: 18 Jul 2019; Revised: 27 Aug 2019; Accepted: 13 Sep 2019; Published: 1 Apr 2020; Available online: 28 Feb 2020.
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Soluble colloidal manganese dioxide was formed by reduction of potassium permanganate with sodium thiosulphate in neutral aqueous medium at 25ºC. The obtained nanosized colloidal manganese dioxide was found to be dark reddish brown in color and stable for several months. The formation of manganese dioxide was confirmed by UV-visible spectrophotometer and determination of oxidation state of Mn species in manganese dioxide. The effect of different concentration of sodium thio sulphate on formation of manganese dioxide was also studied. The nanosized colloid manganese dioxide was characterized by transmission electron microscopy and Fourier transform infrared spectrophotometer. The formed soluble colloidal manganese dioxidewas used as an oxidant in oxidation of ciprofloxacin in perchloric acid medium at 35 ºC. The reaction was first order with respect to concentration of manganese dioxide and hydrogen ion but fractional order with ciprofloxacin. The results suggest formation of complex between ciprofloxacin and manganese dioxide. The oxidation products were also identified on the basis of stoichiometric and characterization results. Mechanistic scheme is conforming with the observed kinetics has been proposed with following rate law



Soluble colloidal manganese dioxide; Ciprofloxacin; Characterization; Kinetics; Oxidation.

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